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Tocris/U 73343/4133/50/50 mg

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Tocris Bioscience

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4133/50

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Description:AnalogofU73122(Cat.No.1268)

ChemicalName:1-[6-[[(17β)-3-Methoxyestra-1,3,5(10)-trien-17-yl]amino]hexyl]-2,5-pyrrolidinedione

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

AnalogofU73122(Cat.No.1268);canbeusedasanegativecontrol.InhibitsPanx1currentsinHEKcells.Alsoinhibitsvasopressin-andGTPγS-inducedCa²⁺influxinhepatocytes.

TechnicalData

M.Wt	466.66
Formula	C₂₉H₄₂N₂O₃
Storage	StoreatRT
Purity	≥98%(HPLC)
CASNumber	142878-12-4
PubChemID	114825
InChIKey	CJHWFIUASFBCKN-ZRJUGLEFSA-N
Smiles	[H][C@]23[C@@]([C@]([H])(CC[C@@H]4NCCCCCCN5C(CCC5=O)=O)[C@]4(C)CC3)([H])CCC1=CC(OC)=CC=C12

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	4.67	10mMwithgentlewarming
	ethanol	2.33	5mMwithgentlewarming

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight466.66.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.14mL	10.71mL	21.43mL
5mM	0.43mL	2.14mL	4.29mL
10mM	0.21mL	1.07mL	2.14mL
50mM	0.04mL	0.21mL	0.43mL

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