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Tocris/A 350619 hydrochloride/2753/50/50 mg
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Description:Solubleguanylylcyclase(sGC)activator
ChemicalName:3-[2-[(4-Chlorophenyl)thiophenyl]-N-[4-(dimethylamino)butyl]-2-propenamidehydrochloride
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
Activatorofsolubleguanylylcyclase(sGC).ActivatesbasalsGCandsynergisticallyactivatessGCinthepresenceofNO.Relaxescavernosumsmoothmuscleinvitroandinducespenileerectionsinrats.Inducesasustainedincreaseinskinbloodflowinvivo.
TechnicalData
M.Wt | 425.41 |
Formula | C21H25ClN2OS.HCl |
Storage | Storeat+4°C |
Purity | ≥99%(HPLC) |
CASNumber | 1217201-17-6 |
PubChemID | 56924282 |
InChIKey | PDVBHWZPRQFKJS-KYIGKLDSSA-N |
Smiles | O=C(NCCCCN(C)C)/C=C/C1=C(SC2=CC=C(Cl)C=C2)C=CC=C1.Cl |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
water | 42.54 | 100 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight425.41.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 2.35mL | 11.75mL | 23.51mL |
5mM | 0.47mL | 2.35mL | 4.7mL |
10mM | 0.24mL | 1.18mL | 2.35mL |
50mM | 0.05mL | 0.24mL | 0.47mL |
MolarityCalculator
MolarityCalculator
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ReconstitutionCalculator
ReconstitutionCalculator
DilutionCalculator
DilutionCalculator
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ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet
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