商品信息
联系客服
郑重提醒:
无质量问题不接受退换货,下单前请仔细核对信息。
下单后请及时联系客服核对商品价格,订单生效后再付款。
Tocris/AR-C 102222/3969/50/50 mg
免费咨询热线
4000-520-616
Description:SelectiveiNOSinhibitor
ChemicalName:5-[(4'-Amino-5',8'-difluorospiro[piperidine-4,2'(1'H)-quinaxolin]-1-yl)carbonyl]-2-pyridinecarbonitrilehydrochloride
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
InducIBLenitricoxidesynthase(iNOS)inhibitor;selectiveforiNOSovereNOS(IC50valuesare0.037and>100μMforiNOSandeNOSrespectively).Exhibitsantinociceptiveandanti-inflammatoryactivityinrodentpainmodels.
LicensingInformation
SoldwiththepermissionofAstraZenecaUKLtd.
TechnicalData
M.Wt | 418.83 |
Formula | C19H16F2N6O.HCl |
Storage | Storeat+4°C |
Purity | ≥98%(HPLC) |
CASNumber | 253771-21-0 |
PubChemID | 21192822 |
InChIKey | FJFMOBYDHGJDGV-UHFFFAOYSA-N |
Smiles | O=C(C4=CC=C(C#N)N=C4)N(CC3)CCC23N=C(N)C1=C(F)C=CC(F)=C1N2.Cl |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 41.86 | 100 | |
water | 10.47 | 25 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight418.83.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 2.39mL | 11.94mL | 23.88mL |
5mM | 0.48mL | 2.39mL | 4.78mL |
10mM | 0.24mL | 1.19mL | 2.39mL |
50mM | 0.05mL | 0.24mL | 0.48mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
DilutionCalculator
DilutionCalculator
Calculatethedilutionrequiredtoprepareastocksolution.
ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet
▍
品牌分类
▍
官网分类
▍
品牌问答
暂无品牌问答