TocrisX中国代理价格，厂家 Tocris信号通路抑制剂,Tocris/AM 114/2564/10/10 mg,蛋白酶类,酶,蛋白类,,Tocris Bioscience蚂蚁淘商城

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Tocris/AM 114/2564/10/10 mg

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Tocris Bioscience

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2564/10

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4000-520-616

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Description:20Sproteasomeinhibitor

ChemicalName:3,5-Bis-[benzylidene-4-boronicacid]-1-methylpiperidin-4-one

Purity:≥97%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Inhibitorofthechymotrypsin-likeactivityofthe20Sproteasome(IC₅₀~1μM).Displaysanticanceractivity;inhibitscellgrowthinhumancoloncancerHCT116p53+/+cells(IC₅₀=1.49μM).

LicensingInformation

SoldwiththepermissionofJohnsHopkinsUniversity

TechnicalData

M.Wt	377.01
Formula	C₂₀H₂₁B₂NO₅
Storage	Storeat+4°C
Purity	≥97%(HPLC)
CASNumber	856849-35-9
PubChemID	11639443
InChIKey	SRPIKXGUPAKTIZ-OTYYAQKOSA-N
Smiles	O=C(/C(CN(C)C3)=C/C2=CC=C(B(O)O)C=C2)/C3=C/C1=CC=C(B(O)O)C=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	DMSO	3.77	10

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight377.01.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.65mL	13.26mL	26.52mL
5mM	0.53mL	2.65mL	5.3mL
10mM	0.27mL	1.33mL	2.65mL
50mM	0.05mL	0.27mL	0.53mL

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