Tocris公司代理生物计划 Tocris Bioscience型号参数规格,Tocris/Nigericin sodium salt/4312/10/10 mg,转运体,生物分子,生化试剂,,Tocris Bioscience蚂蚁淘商城

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Tocris/Nigericin sodium salt/4312/10/10 mg

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Tocris/Nigericin sodium salt/4312/10/10 mg

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Tocris Bioscience

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4312/10

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4000-520-616

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Description:SelectiveK⁺ionophore

ChemicalName:(2R)-2-[(2R,3S,6R)-6-[[(2S,4R,5R,7R,9R,10R)-2-[(2R,5S)-5-[(2R,3S,5R)-5-[(2S,3S,5R,6R)-6-Hydroxy-6-(hydroxymethyl)-3,5-dimethyl-2-tetrahydropyranyl]-3-methyl-2-tetrahydrofuranyl]-5-methyl-2-tetrahydrofuranyl]-9-methoxy-2,4,10-trimethyl-1,6-dioxaspiro[4.5]decan-7-yl]methyl]-3-methyl-2-tetrahydropyranyl]propanoicacidsodiumsalt

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potassiumionophore,exchangesK⁺forH⁺acrossbiologicalmembranes,inasimilarmannertoValinomycin(Cat.No.3373).StimulatesmitochondralATPaseactivityanddisruptsmembranepotential.AlsoactsasanionophoreforPb²⁺withnoactivitywithotherdivalentcations.AntibioticderivedfromStreptomyceshygroscopius.

TechnicalData

M.Wt	746.94
Formula	C₄₀H₆₇NaO₁₁
Storage	Storeat-20°C
CASNumber	28643-80-3
PubChemID	16760591
InChIKey	MOYOTUKECQMGHE-PDEFJWSRSA-M
Smiles	[Na+].[H][C@@]1(C[C@H](C)[C@@]([H])(O1)[C@]1(C)CC[C@@]([H])(O1)[C@]1(C)C[C@@H](C)[C@]2(O1)O[C@]([H])(C[C@@]1([H])CC[C@H](C)[C@@]([H])(O1)[C@@H](C)C([O-])=O)C[C@@H](OC)[C@H]2C)[C@@]1([H])O[C@@](O)(CO)[C@H](C)C[C@@H]1C

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	ethanol	74.69	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight746.94.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	1.34mL	6.69mL	13.39mL
5mM	0.27mL	1.34mL	2.68mL
10mM	0.13mL	0.67mL	1.34mL
50mM	0.03mL	0.13mL	0.27mL

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BiologicalActivity

TechnicalData

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