品牌试剂实验Tocris代理 Tocris Bioscience型号参数规格,Tocris/Nonactin/2505/10/10 mg,转运体,生物分子,生化试剂,,Tocris Bioscience蚂蚁淘商城

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Tocris/Nonactin/2505/10/10 mg

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Tocris Bioscience

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2505/10

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4000-520-616

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Description:Monovalentcationionophore

AlternativeNames:AmmoniumIonophoreI

ChemicalName:(1R,2R,5R,7R,10S,11S,14S,16S,19R,20R,23R,25R,28S,29S,32S,34S)-2,5,11,14,20,23,29,32-Octamethyl-4,13,22,31,37,38,39,40-octaoxapentacyclo[32.2.1.17,10.116,19.125,28]tetracontane-3,12,21,30-tetrone

Purity:≥93%

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

MonovalentcationionophorethatdisplaysselectivityforK⁺andNH₄⁺(K⁺=NH₄⁺>Na⁺>Mg²⁺>Li⁺>>Ca²⁺fornonactin-EVAsensor).Inducescationtransportacrossartificialmembranes.AlsoinhibitsP-glycoprotein-mediatedeffluxofchemotherapeuticagentsinmultiple-drugresistantcancercells.Antibiotic.

TechnicalData

M.Wt	736.94
Formula	C₄₀H₆₄O₁₂
Storage	Desiccateat-20°C
Purity	≥93%
CASNumber	6833-84-7
PubChemID	72519
InChIKey	RMIXHJPMNBXMBU-QIIXEHPYSA-N
Smiles	[H][C@]3(CC[C@@](C[C@@H](C)OC([C@H](C)[C@@]4([H])CC[C@](C[C@H](C)OC([C@H]5C)=O)([H])O4)=O)([H])O3)[C@H](C)C(O[C@@H](C)C[C@@]1([H])O[C@]([C@@H](C)C(O[C@H](C)C[C@]2([H])O[C@@]5([H])CC2)=O)([H])CC1)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	ethanol	7.37	10

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight736.94.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	1.36mL	6.78mL	13.57mL
5mM	0.27mL	1.36mL	2.71mL
10mM	0.14mL	0.68mL	1.36mL
50mM	0.03mL	0.14mL	0.27mL

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BiologicalActivity

TechnicalData

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