BiologicalActivity
Apotentandselectiveinhibitoroftheanandamidemembranetransporter(AMT)withIC50valuesof4-11μM.DisplaysnegligIBLeagoNISTactivityatthehVR1receptorandveryweakactionatCB1andCB2receptors.Kivaluesare>5-10μMatCB1andCB2.Activeinvivo.Alsoavailableinwater-solubleemulsion(Cat.No.1686).
TechnicalData
| M.Wt | 409.61 |
| Formula | C27H39NO2 |
| Storage | Desiccateat-20°C |
| Purity | ≥98%(HPLC) |
| CASNumber | 313998-81-1 |
| PubChemID | 9887748 |
| InChIKey | WUZWFRWVRHLXHZ-ZKWNWVNESA-N |
| Smiles | O=C(NC1=C(C)C=C(O)C=C1)CCCC=C/CC=C/C/C=CC/C=CCCCCC |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solubility | Solubleinethanol(suppliedpre-dissolvedinanhydrousethanol,5mg/ml) |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight409.61.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 2.44mL | 12.21mL | 24.41mL |
| 5mM | 0.49mL | 2.44mL | 4.88mL |
| 10mM | 0.24mL | 1.22mL | 2.44mL |
| 50mM | 0.05mL | 0.24mL | 0.49mL |
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