BiologicalActivity
Dualserotonin/noradrenalinre-uptakeinhibitorthatdisplays~30-foldhigheraffinityforSERTthanNET(Kivaluesare82and2480nMrespectively).Antidepressant;increasesswimmingandclimbingbehaviorintheforced-swimtestinrats.
CompoundLibraries
VenlafaxinehydrochlorideisalsoofferedaspartoftheTocriscreenPlusandTocriscreenLibraryofFDA-ApprovedCompounds.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
TechnicalData
| M.Wt | 313.86 |
| Formula | C17H27NO2.HCl |
| Storage | StoreatRT |
| Purity | ≥99%(HPLC) |
| CASNumber | 99300-78-4 |
| PubChemID | 62923 |
| InChIKey | QYRYFNHXARDNFZ-UHFFFAOYSA-N |
| Smiles | OC2(CCCCC2)C(CN(C)C)C1=CC=C(OC)C=C1.Cl |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 15.69 | 50 | |
| ethanol | 31.39 | 100 | |
| water | 31.39 | 100 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight313.86.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 3.19mL | 15.93mL | 31.86mL |
| 5mM | 0.64mL | 3.19mL | 6.37mL |
| 10mM | 0.32mL | 1.59mL | 3.19mL |
| 50mM | 0.06mL | 0.32mL | 0.64mL |
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