LKT/HYDROCORTISONE 21-ACETATE/H9612/1 g
- Description
- Product Info
- Shipping and Storage
- Downloads
- References
Description
Hydrocortisone is a steroid hormone that is produced in the adrenal cortex and is involved in stress signaling. Hydrocortisone is a glucocorticoid and is also known as cortisol in its endogenous form; it exhibits anti-inflammatory and immunomodulatory activities. Hydrocortisone is clinically used to treat eczema, psoriasis, gout, and severe allergic reactions. Hydrocortisone stimulates gluconeogenesis, inhibits inflammatory cytokine production, and shifts the immune response from Th1 to Th4 subtype.
Product Info
50-03-3 |
≥98% |
C23H32O6 |
404.50 |
(11β)11,17,21-Trihydroxypregn-4-ene-3,20-dione 21-acetate |
[2-[(8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate |
Colifoam; Cortaid; Cortifoam; Hydrocal; Lanacort; Sigmacort; Velopural |
223°C(dec) |
Soluble in DMF and dioxane. Slightly soluble in chloroform, ethanol (4 mg/mL), methanol. ether and water. |
White Crystal Powder |
Shipping and Storage
Ambient |
Ambient |
Downloads
H9612 MSDS PDF |
H9612 Info Sheet PDF |
References
Angelier F, Wingfield JC. Importance of the glucocorticoid stress response in a changing world: theory, hypotheses and perspectives. Gen Comp Endocrinol. 2013 Sep 1;190:118-28. PMID: 23770214.
Tarchalska-Kryńska B. Glucocorticosteroids: mechanism of action, pharmacological effects, pharmacokinetics and adverse effects. Otolaryngol Pol. 1994;48 Suppl 17:41-8. PMID: 8090502.
Sluyser M. Mechanism of steroid hormone action at the cellular level. Basic Life Sci. 1975;6:79-104. PMID:168860.
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