Technical DocumentsDescriptionDetailsIntellectual PropertyRelated ProductsTechnical DocumentsSafety Data SheetGlen Report 20.25: New Universal Support - Glen UnySupportGlen Report 23.29: New Products - Bulk Polystyrene SupportsGlen Report 10.15: Universal Support Replaces Individual ColumnsDescriptionSome of our more popular minor base and modifier supports are available on polystyrene in columns fully compatible with the Applied Biosystems 3900 synthesizer. These include our popular Universal Support III, which will allow DNA, RNA or LNA oligos to be produced on the 3900 with ANY base at the 3" terminus. At the same time, we are offering 1 μmole columns of Universal Support III for the 3900 instrument. Structures and more complete descriptions are found in the relevant catalog sections for each item. AB 3900 columns can be prepared with virtually any of the CPG supports in this catalog.It is no longer necessary to adjust the flow using our AB 3900 CPG columns, as noted in the box to the right.Modified CPG columns are only available in 200 nmole size -simple add ‘A’ to the regular catalog number to order.DetailsUsageCoupling: This support should be used in a manner identical to normal protected nucleoside support since it contains the DMT group.Deprotection: Solution phase:Ammonium Hydroxide:MethylAmine (AMA) 1:1 for 1 hour at 65°C or Ammonium Hydroxide for 8 hours at 55°C. For sensitive minor bases or dyes, Glen UnySupport may be eliminated with 50 mM Potassium Carbonate in Methanol in 17 hours at room temperature or with Tert-Butylamine/water 1:3 (v/v) for 4 hours at 60°C.Gas Phase:Methylamine gas for 30 minutes at 65°C at 30 psi.SpecificationsStorageControlled room temperature or lower, dryIntellectual PropertyThis product is covered by US Patent 7,202,264 owned by Ionis Pharmaceuticals, Inc..Related Products/*.carousel-inner .active.left{ left: -33%; }*//*.carousel-inner .active.right { left: 33%;}*//*.carousel-inner .next { left: 33% }*//*.carousel-inner .prev { left: -33%}*//*.carousel-control.left{ background-image: none; position: relative; float: left; }*//*.carousel-control.right { background-image: none; position: relative; float: right;}*//*.carousel-inner .item { background: white;}*//*.block.upsell {display: none; }*//*.products .product-item-details {*//*padding-left: 10px;*//*padding-right: 10px;*//*background: #efeeee;*//*color: #58595b;*//*font-size: 18px;*//*padding: 20px 10px;*//*border-radius: 0 0 3px 3px; }*//*.owl-wrapper-outer{*//*overflow: hidden;*//*position: relative;*//*width: 100%;*//*}*//*.block.related .owl-carousel .owl-item {*//*padding: 0px 7px;*//*}*/Related Products Universal Support III PSCatalog #: 26-5010Glen UnySupport™ 500Catalog #: 20-5040Glen UnySupport™ 1000Catalog #: 20-5041Glen UnySupport™ FCCatalog #: 22-50413"-Phosphate CPGCatalog #: 20-29003"-Spacer C3 CPGCatalog #: 20-2913