提醒：代购产品，无质量问题不接受退换货，下单前请仔细核对信息。下单后请及时联系客服
核对商品价格，订单生效后再付款。
Signalchem/NUAK1, Active/5 ug/N19-10G-05
价格：
自营商城
解放采购
正品保障
及时交付
厂家直采
一站服务
货号：
品牌：
会员服务：
尊享会员价
贵宾专线
运费优惠
闪电退款
福利优惠
上门换新
友情提示
以上价格仅为参考，请联系客服询价。
免费咨询热线
4000-520-616
产品说明
Overview:NUAK1 or SNF1/AMP kinase-related kinase (SNARK) is a member of the NUAK family of SNF1-like kinase 1 that is also known as AMPK-related protein kinase 5 (ARK5). ARK5 is a tumor cell survival factor that is activated by AKT and acts as an ATM kinase under conditions of nutrient starvation (1). NUAK1 is highly expressed in heart and brain, and at lower levels in skeletal muscle, kidney, ovary, placenta, lung, and liver. NUAK1 is involved in tolerance to glucose starvation and suppresses Fas-induced apoptosis by phosphorylation of CASP6, thus suppressing the activation of the caspase and the subsequent cleavage of CFLAR (2). Gene Aliases:ARK5; KIAA0537 Genbank Number:NM_014840 References:1. Suzuki, A. et.al: Identification of a novel protein kinase mediating Akt survival signaling to the ATM protein. J. Biol. Chem. 278: 48-53, 2003.2. Lizcano J.M. et.al: LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1. EMBO J. 23:833-843, 2004.
SignalChem 公司生产和销售创新性的细胞信号研究相关产品。公司专注于生产高纯度的活性重组蛋白,产品广泛应用于基础生物学和药物研究。
新品排行榜
1
Signalchem/PI(3)P:PS/1 ml/P426-5...
2
Signalchem/KIF5B-RET (V804L), Ac...
3
Signalchem/CAMK1 gamma, Active/5...
4
Signalchem/GSK3 beta, Active/5 u...
5
Signalchem/Y1BFP Protein/50 ug/B...
6
Signalchem/AMPK (A1/B1/G1), Acti...
7
Signalchem/Tau-441 (231-441) Pro...
8
Signalchem/CAMK1 gamma, Active/1...
9
Signalchem/HSP90 alpha Protein/2...
10
Signalchem/14-3-3 sigma Protein/...
微信公众号
手机扫码，关注动态