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Signalchem/CK1 gamma 1, Active/10 ug/C68-11G-10
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Overview:CK1γ1 or casein kinase 1, gamma 1 is belonging to the most abundant serine/threonine kinase in eukaryotic cell extracts which is mainly involved in growth and morphogenesis of eukaryotic cells. Casein kinase 1, gamma 1 possesses a C-terminal most terminal sequence motif (MTM), which it shares with CSNK1G2 and CSNK1G3 which is associated with heterologous carboxy-terminal sequences (1). Casein kinase 1-gamma couples Wnt receptor activation to the cytoplasmic signal transduction apparatus (2). Gene Aliases:CK1G1; CSNK1G1; CKI-gamma 1 Genbank Number:NM_022048 References:1. Kusuda, J. et.al: Cloning, expression analysis and chromosome mapping of human casein kinase 1 gamma-1 (CSNK1G1): identification of two types of cDNA encoding the kinase protein associated with heterologous carboxy-terminal sequences. Cytogenet. Cell Genet. 90: 298-302, 2000.2. Davidson, G. et.al: Casein kinase 1-gamma couples Wnt receptor activation to cytoplasmic signal transduction. Nature 438: 867-872, 2005.
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