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Signalchem/CDK2/CyclinO, Active/5 ug/C29-19G-05
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产品说明
Overview:CDK2/CyclinO is a member of the cyclin dependent protein kinase family complexed to CyclinO. CyclinO was used as a specific protein isoform name for the UNG gene which is localized exclusively in the nucleus. In addition, CyclinO was reported to shows significant uracil-DNA glycosylase activity (1). CDK2/CyclinO protein levels increase during G1 phase and the protein is turned over during the course of cell cycle (2). Gene Aliases:CDK2: p33 (CDK2) CyclinO: CCNO; CCNU; UDG2 Genbank Number:NM_001798NM_021147 References:1. Caradonna, S. et.al: Affinity purification and comparative analysis of two distinct human uracil-DNA glycosylases. Exp. Cell Res. 222: 345-359, 1996.2. Muller, S. J. et.al: Cell cycle regulation of a human cyclin-like gene encoding uracil-DNA glycosylase. J. Biol. Chem. 268: 1310-1319, 1993.
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