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Athens Research/Cambio - Excellence in Molecular Biology/0.25g/10-1028-02
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Oligo Synthesis : CEPsPrices quoted are for single packs only. For multiples of the same product please request a quote. Some of Glen"sproductsarehazardousandmay be subject to additional shipping charges. Full product information is available onGlen Research"s website.CatalogueDescriptionProtocolsNotesApplications & Benefits8-oxo-dG-CE Phosphoramidite8-oxo-dG-CE PhosphoramiditeGlen ResearchCatalogue No.DescriptionPack SizePriceQtyChange to:€10-1028-028-oxo-dG-CE Phosphoramidite0.25g£780.00£741.00Offer until : 31-Mar-2021Offer Code : GLEN55% off all Glen productsView OfferQuantityAdd to Order10-1028-908-oxo-dG-CE Phosphoramidite100µmoles£284.00£269.80Offer until : 31-Mar-2021Offer Code : GLEN55% off all Glen productsView OfferQuantityAdd to Order10-1028-958-oxo-dG-CE Phosphoramidite50µmoles£142.00£134.90Offer until : 31-Mar-2021Offer Code : GLEN55% off all Glen productsView OfferQuantityAdd to OrderRelated productsPlease find below the related productsView5,6-Dihydro-dT-CE Phosphoramidite View5,6-Dihydro-dU-CE Phosphoramidite View5-Hydroxymethyl-dU-CE Phosphoramidite View5-OH-dC-CE Phosphoramidite View5-OH-dU-CE Phosphoramidite View8-oxo-dA-CE Phosphoramidite View8-oxo-dG-CE Phosphoramidite 8-oxo-dG-CE Phosphoramidite8-oxo-dG-CE PhosphoramiditeGlen Research 8-oxo-dG-CE PhosphoramiditeCatalog Number: 10-1028-xxDescription: 8-oxo-dG-CE Phosphoramidite5"-Dimethoxytrityl-N2-isobutyryl-8-oxo-deoxyGuanosine-3"-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramiditeFormula: C44H54N7O9PM.W.: 855.93F.W.: 345.21Diluent: Anhydrous AcetonitrileCoupling: No changes needed from standard method recommended by synthesizer manufacturer.Deprotection: Cleave and deprotect with ammonium hydroxide containing 0.25M 2-mercaptoethanol 17 hours at 55°C to avoid oxidative degradation of the 8-oxo-dG site.Storage: Refrigerated storage, maximum of 2-8°C, dryStability in Solution: 24 hoursDNA Damage/RepairCellular DNA is constantly being damaged by oxidation andalkylation, by free radicals, and by ultraviolet and ionizing radiation. Thebody has therefore evolved a number of repair enzyme systems to excise andrepair these lesions. The 8-oxo purine monomers allow investigation of thestructure and activity of oligonucleotides containing an 8-oxo mutation which isformed naturally when DNA is subjected to oxidative conditions or ionizingradiation. 5,6-Dihydro pyrimidines are naturally occurring compounds that arestructural components of alanine transfer RNA. Dihydrouracil and the hydroxypyrimidines are major base damage products formed by exposure of DNA to ionizingradiation.If you cannot find the answer to your problem below then please contact us or telephone 01954 210 2008-oxo-dG-CE Phosphoramidite8-oxo-dG-CE PhosphoramiditeGlen ResearchMSDSGlen Report 7.1: NEW MINOR BASESIf you cannot find the answer to your problem below then please contact us or telephone 01954 210 2008-oxo-dG-CE Phosphoramidite8-oxo-dG-CE PhosphoramiditeGlen ResearchSynthetic oligonucleotides containing 8-oxo-dG must be cleaved and deprotected with ammonium hydroxide containing 0.25M 2-mercaptoethanol to avoid oxidative degradation of 8-oxo-dG sites.Frequently Asked Technical QuestionQUESTION: How do you deprotect 8-oxo-dG?RESPONSE:Cleave and deprotect with ammonium hydroxide containing 0.25M 2-mercaptoethanol 17 hours at 55°C to avoid oxidative degradation of the 8-oxo-dG siteIf you cannot find the answer to your problem below then please contact us or telephone 01954 210 2008-oxo-dG-CE Phosphoramidite8-oxo-dG-CE PhosphoramiditeGlen ResearchEXTINCTION DATAItemNucleosideλMax-1Emax-1λMax-2Emax-2E260(nm)(ml/µmole)nm(ml/µmole)(ml/µmole)10-10288-oxo-dG2945.22506.75.9DILUTION/COUPLING DATAThe table below shows pack size data and, for solutions, dilutions and approximate couplings based on normal priming procedures. Please link for more detailed usage information with the various synthesizers.ABI 392/394Cat.No.PackSizeGrams/Pack0.1M Dil.(mL)LV40LV20040nm0.2µm1µm10µmApproximate Number of Additions10-1028-020.25grams.25grams2.928450.431.522.9116.84.210-1028-90100µmoles.086grams120127.55.454110-1028-9550µmoles.043grams.53.3321.25.91.67.17ExpediteCat.No.PackSizeGrams/PackDilution(mL)Molarity50nm0.2µm1µm15µmApproximate Number of Additions10-1028-020.25grams.25grams4.36.0780.850.536.735.0510-1028-90100µmoles.086grams1.5.0723.614.7510.731.4810-1028-9550µmoles.043grams.75.078.65.383.91.54BeckmanCat.No.PackSizeGrams/PackDilution(mL)Molarity30nm200nm1000nmApproximate Number of Additions10-1028-020.25grams.25grams4.36.0782.451.537.4510-1028-90100µmoles.086grams1.5.0725.215.7511.4510-1028-9550µmoles.043grams.75.0710.26.384.64If you cannot find the answer to your problem below then please contact us or telephone 01954 210 200
Athens Research & Technology—供应多款蛋白、酶制品
Athens Research & Technology是成立于2010年的新兴生物高科技制品公司，该公司拥有BSL-2实验室及超过11000平方英尺的cGMP生产厂房，并且通过ISO 9001：2008认证。Athens公司致力于纯化分离高纯度，高活性的人类蛋白质及研发多克隆抗血清产品。提供包括高纯度及活性的丝氨酸蛋白酶，蛋白酶抑制剂，中性粒细胞酶，载脂蛋白，脂蛋白，血小板蛋白，转铁蛋白，免疫球蛋白等等。公司产品适用于炎症，冠状动脉疾病，自身免疫性疾病，癌症，阿尔茨海默氏病等众多研究领域，已被世界*制药公司及诊断试剂公司用于体外诊断试剂盒/免疫检测试剂盒、药物筛选、细胞培养液（包括干细胞）等产品研发。除了人类蛋白质，我们还从动物血清和组织中分离多种蛋白质及酶类。此外，Athens Research and Technology还提供特殊试剂/蛋白定制服务，以满足研究人员的不同需求。
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