Catalogue numberPRO-2232 SynonymsDecorin, Decorin Proteoglycan, Bone Proteoglycan II, SLRR1B,PG-S2, CSCD, PG40,Dermatan Sulphate Proteoglycans II, Small Leucine-RichProtein 1B, Proteoglycan Core Protein, DSPG2, PGII, PGS2, Decorin, Boneproteoglycan II, PG-S2, , PG40.IntroductionDecorin (DCN) is a small cellular or pericellular matrix proteoglycan which is closely related in structure to biglycan protein. Decorin is a secreted protein which binds to collagen and fibronectin in extracellular matrix. Decorin appears in different glycoforms, substituted with chondroitin sulfate or dermatan sulfate consistent with the original tissue. DCN contains one attached glycosaminoglycan chain. Decorin influences the rate of fibril formation. Decorin is capable of suppressing the growth of various tumor cell lines. DCN gene defects cause corneal dystrophy. The DCN gene is a candidate gene for Marfan syndrome.DescriptionDCN produced in Sf9 Baculovirus cells is a single,glycosylated polypeptide chain containing 335 amino acids (31-359a.a.) andhaving a molecular mass of 37.1kDa.(Molecular size on SDS-PAGE will appear atapproximately 40-57kDa).DCN is expressed with a 6 amino acid His tag atC-Terminus and purified by proprietary chromatographic techniques.SourceSf9,Baculovirus cells.Physical AppearanceSterile filtered colorless solution.FormulationDCN protein solution (1mg/ml) contains Phosphate BufferedSaline (pH 7.4) and 10% glycerol.StabilityStore at 4°C if entire vial will be used within 2-4 weeks.Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.PurityGreater than 95% as determined by SDS-PAGE.Amino acid sequenceDEASGIGPEV PDDRDFEPSL GPVCPFRCQC HLRVVQCSDL GLDKVPKDLPPDTTLLDLQN NKITEIKDGD FKNLKNLHAL ILVNNKISKV SPGAFTPLVK LERLYLSKNQ LKELPEKMPKTLQELRAHEN EITKVRKVTF NGLNQMIVIE LGTNPLKSSG IENGAFQGMK KLSYIRIADTNITSIPQGLP PSLTELHLDG NKISRVDAAS LKGLNNLAKL GLSFNSISAVDNGSLANTPH LRELHLDNNK LTRVPGGLAE HKYIQVVYLH NNNISVVGSS DFCPPGHNTK KASYSGVSLFSNPVQYWEIQ PSTFRCVYVR SAIQLGNYKH HHHHH.Safety Data SheetSDSUsageProspec"s products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
ProSpec-Tany TechnoGene Ltd.公司创立人Dr. Tanchum (Tany) Amarant 主要致力于蛋白生物化学方面的研究工作，1947年出生于以色列。1991-1997创建ReProGen 公司，从事细胞因子和趋化因子的大量生产及纯化；1997-2000创建ProSpec-TechnoGene，主要生产用于生命科学研究的各种重组蛋白及相关抗体。拥有专利United States Patent 5434135。
ProSpec is an evolving biotech company providing highly purified proteins worldwide which serve the research community with cytokine-related products for cancer, apoptosis, development, endocrinology, immunology, neuroscience, proteases, and stem cell research.
Among our proteins are Interferons, Interleukins, Bone Morphogenic Proteins, Tumor Necrosis factors, Leptins, Stem Cell factors, Prolactins, Chemokines, Antibodies, Peptides, Enzymes, Viral Antigens, various growth factors such as: Platelet Derived, Epidermal, Insulin Like, Nerve, Connective Tissue, Vascular Endothelial, Fibroblast and more.....
Our research team and scientists have been able to assemble more than 1700 recombinant proteins, peptides and antibodies for your research needs. The proteins are rigorously tested to meet the research and development demand for excellent quality, uncompromising biological activity at competitive prices.
ProSpec has established sterling reputation among the scientific community, a reputation built on innovative products, customer service and attention to detail. Our reputation for quality is an essential factor in achieving a favorable position in the market place and the benefits associated with manufacturing top quality products.
