首页 > StressMarq > StressMarq/Anti-20S Proteasome Antibody/SPC-215D-ALP/100-µl

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StressMarq/Anti-20S Proteasome Antibody/SPC-215D-ALP/100-µl

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SPC-215D-ALP

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Overview:ProductName20SProteasomeAntibodyDescriptionRabbitAnti-Human20SProteasomePolyclonalSpeciesReactivityHuman,MouseApplicationsWB,ICC/IF,IPAntibodyDilutionWB(1:5000);optimaldilutionsforassaysshouldbedeterminedbytheuser.HostSpeciesRabbitImmunogenSpeciesHumanImmunogenHuman20SproteasomeextractedfromerythrocytesConjugatesAlkalinePhosphatase,APC,ATTO390,ATTO488,ATTO565,ATTO594,ATTO633,ATTO655,ATTO680,ATTO700,Biotin,FITC,HRP,PE/ATTO594,PerCP,RPE,Streptavidin,UnconjugatedPropertiesStorageBufferRabbitAntiserum,0.1%sodiumazideStorageTemperature4ºCShippingTemperatureBlueIceor4ºCPurificationRabbitantiserumClonalityPolyclonalSpecificityDetectsmultiple20Sproteasomesubunits.CiteThisProductStressMarqBiosciencesCat#SPC-215,RRID:AB_2704379CertificateofAnalysisA1:1000dilutionofSPC-215wassufficientfordetectionof20Sproteasome‘core’subunitsin0.1µgofhuman26SproteasomebyelectRochemiluminescenceanalysisusinggoatanti-rabbitIgG:HRPasthesecondaryantibody.BIOLOGicalDescriptionAlternativeNames20ScoreparticleAntibody,MacropainAntibody,MulticatalyticendopeptidasecomplexsubunitAntibody,ProsomesubunitAntibody,Proteasomesubunitalphatype1Antibody,Proteasomesubunitalphatype5Antibody,Proteasomesubunitalphatype7Antibody,ProteasomesubunitAntibody,Proteasomesubunitbetatype1Antibody,Proteasomesubunitbetatype5Antibody,Proteasomesubunitbetatype6Antibody,Proteasomesubunitbetatype7Antibody,PSMA1Antibody,PSMA5Antibody,PSMA7Antibody,PSMB1Antibody,PSMB5Antibody,PSMB6Antibody,PSMB7Antibody,ZETAAntibodyResearchAreasCancer,ApoptosisCellularLocalizationCytoplasmScientificBackgroundProteasomesfunctioninthedegradationofunusableordamagedcellularproteins.Proteasomecomplexesarethereforelocalizedinthenucleusandcytoplasmofeukaryoticcells.Themostcommonlyfoundproteasomeinmammaliancytosolisthe26Sproteasome,whichismadeupofone20Sproteasomecoresubunitandtwo19Ssubunits.The20Scoreparticleisinitselfmadeupoftwoalphasubunitsandtwobetasubunits,whichrepresentthecatalyticcomponent.Proteinsdestinedfordegradationarefirstlabeledbypolyubiquitinationbeforetheyentertheproteasomecoreandarebrokendown.References1.SaekiY.,&TanakaK.(2012)MethodsMolBiol.832:315-37.2.GengF.,WenzelS.,&TanseyW.(2012)AnnuRevBiochem.81:177-201.ProductImagesCurrentlytherearenoimagesforthisproductProductCitations(0)Currentlytherearenocitationsforthisproduct.AP(AlkalinePhosphatase)Properties:Broadenzymaticactivityforphosphateestersofalcohols,amines,pyrophosphate,andphenolsCommonlyusedtodephosphorylatethe5’-terminiofDNAandRNAtopreventself-ligationCatalyzestheconversionof:Chromogenicsubstrates(e.g.pNPP,naphtholAS-TRphosphate,BCIP)intocolouredproductsFluorogenicsubstrates(e.g.4-methylumbelliferylphosphate)intofluorescentproductsMolecularweight:140kDaApplications:Westernblot,immunohistochemistry,andELISAAPDatasheet

StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。