首页 > StressMarq > StressMarq/Anti-CaMKI Antibody (pThr177)/SPC-930D-A680/100-µl

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StressMarq/Anti-CaMKI Antibody (pThr177)/SPC-930D-A680/100-µl

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SPC-930D-A680

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Overview:ProductNameCaMKIAntibody(pThr177)DescriptionRabbitAnti-HumanCaMKI(pThr177)PolyclonalSpeciesReactivityHumanApplicationsWB,AMAntibodyDilutionWB(1:250);optimaldilutionsforassaysshouldbedeterminedbytheuser.HostSpeciesRabbitImmunogenSpeciesHumanImmunogenAphospho-specificpeptidecorrespondingtoresiduessurroundingThr177ofhumanCaMK1(AA174-180)ConjugatesAlkalinePhosphatase,APC,ATTO390,ATTO488,ATTO565,ATTO594,ATTO633,ATTO655,ATTO680,ATTO700,Biotin,FITC,HRP,PE/ATTO594,PerCP,RPE,Streptavidin,UnconjugatedPropertiesStorageBufferPBSpH7.4,50%glycerol,0.025%ThimerosalStorageTemperature-20ºCShippingTemperatureBlueIceor4ºCPurificationPeptideAffinityPurifiedClonalityPolyclonalSpecificityDetects41.337kDa.CiteThisProductStressMarqBiosciencesCat#SPC-930,RRID:AB_2707139CertificateofAnalysisA1:250dilutionofSPC-930wassufficientfordetectionofCaMKI(pThr177)in10µgofhumanbrainlysatebyECLimmunoblotanalysisusinggoatanti-rabbitIgG:HRPasthesecondaryantibody.BIOLOGicalDescriptionAlternativeNamesCalcium/calmodulindependentproteinkinasetype1Antibody,CaMK1Antibody,CaMkinase1alphaAntibody,CaM-KIAntibody,CaMK1alphaAntibody,CaMKI-alphaAntibody,KCC1A_HUMANAntibodyResearchAreasCardiovascularSystem,CellSignaling,Heart,Hypertrophy,Neuroscience,NeurotransmitterReceptorsCellularLocalizationCytoplasm,NucleusAccessionNumberNP_003647GeneID8536SwissProtQ14012ScientificBackgroundCalcium/calmodulin-dependentkinases(CaMKs)areasubfamilyoftheserine/threonineproteinkinasefamilythatincludesCaMKI,CaMKII,andCaMKIV.TherehavebeenidentifiedmultiplesubstratesforCaMKI,includingsynapsin1,synapsin2,CREB,andCFTR,anditsactivationisdependentuponphosphorylationofThr177byCaMKkinase(CaMKK).StudiessuggestthatCaMKIplaysanimportantroleinretinalfunctionanditsexpressionisregulatedbylightstimulation.ProductImagesCurrentlytherearenoimagesforthisproductProductCitations(0)Currentlytherearenocitationsforthisproduct. ATTO680Overview:HighfluorescenceyieldExcellentthermalandphotostABIlityQuenchedbyelectrondonorsVeryhydrophilicGoodsolubilityinpolarsolventsZwitterionicdyeMolarMass:631g/molATTO680Datasheet OpticalProperties:λex =680nmλem=700 nmεmax=1.25×105Φf= 0.30τfl =1.7nsBrightness=37.5Laser =633 –676nmFilterset =Cy®5.5

StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。