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StressMarq/Anti-CDK7 Antibody/SPC-1115D-P594/100-µl

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SPC-1115D-P594

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Overview: Product Name CDK7 Antibody DescriptionRabbit Anti-Human CDK7 Polyclonal Species Reactivity Human Applications WB, AM Antibody Dilution WB (1:250); optimal dilutions for assays should be determined by the user. Host Species Rabbit Immunogen Species Human Immunogen A synthetic peptide of human CDK7 (AA 325-338) Conjugates Alkaline Phosphatase, APC, ATTO 390, ATTO 488, ATTO 565, ATTO 594, ATTO 633, ATTO 655, ATTO 680, ATTO 700, Biotin, FITC, HRP, PE/ATTO 594, PerCP, RPE, Streptavidin, Unconjugated Properties Storage Buffer PBS pH7.4, 50% glycerol, 0.025% Thimerosal Storage Temperature -20ºC Shipping Temperature Blue Ice or 4ºC Purification Peptide Affinity Purified Clonality Polyclonal Specificity Detects ~39kDa. Cite This Product StressMarq Biosciences Cat# SPC-1115, RRID: AB_2710469 Certificate of Analysis A 1:250 dilution of SPC-1115 was sufficient for detection of CDK7 in 10 µg of HeLa cell lysate by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody. Biological Description Alternative Names 39 kDa protein kinase Antibody, CAK Antibody, CAK1 Antibody, Cdk activating kinase Antibody, CDK7_HUMAN Antibody, Cell division protein kinase 7 Antibody, Cyclin dependent kinase 7 Antibody, HCAK Antibody, MO15 Antibody, P39 Mo15 Antibody, Serine threonine kinase Stk1 Antibody, STK1 Antibody, TFIIH basal transcription factor complex kinase subunit Antibody Cellular Localization Nucleus Accession Number NP_001790 Gene ID 1022 Swiss Prot P50613 Scientific Background CDK7 is a protein-serine/threonine kinase. CDK7 has been identified as the mammalian homolog of MO15, a protein kinase demonstrated in starfish and Xenopus. The regulatory subunit is a novel cyclin (cyclin H) and is required for activation of CDK7. Like other Cdks, CDK7 contains a conserved threonine residue required for full activity; mutation of this residue severely reduces CAK activity. Product Images Currently there are no images for this product Product Citations (0) Currently there are no citations for this product. PE/ATTO 594PE/ATTO 594 is a tandem conjugate, where PE is excited at 535 nm and transfers energy to ATTO 594 via FRET (fluorescence resonance energy transfer), which emits at 627 nm.Overview:High fluorescence yieldHigh photostabilityVery hydrophilicExcellent solubility in waterVery little aggregationPE/ATTO 594 DatasheetOptical Properties:λex = 535 nmλem = 627 nmLaser = 488 to 561 nm

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