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StressMarq/Anti-CDK9 Antibody (pSer347)/SPC-946D-STR/100-µl
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产品说明
Overview:
Product Name
CDK9 Antibody (pSer347)
DescriptionRabbit Anti-Human CDK9 (pSer347) Polyclonal
Species Reactivity
Human
Applications
WB, AM
Antibody Dilution
WB (1:250); optimal dilutions for assays should be determined by the user.
Host Species
Rabbit
Immunogen Species
Human
Immunogen
A phospho-specific peptide corresponding to residues surrounding Ser347 of human CDK9 (AA344-350)
Conjugates
Alkaline Phosphatase, APC, ATTO 390, ATTO 488, ATTO 565, ATTO 594, ATTO 633, ATTO 655, ATTO 680, ATTO 700, Biotin, FITC, HRP, PE/ATTO 594, PerCP, RPE, Streptavidin, Unconjugated
Properties
Storage Buffer
PBS pH7.4, 50% glycerol, 0.025% Thimerosal
Storage Temperature
-20ºC
Shipping Temperature
Blue Ice or 4ºC
Purification
Peptide Affinity Purified
Clonality
Polyclonal
Specificity
Detects 42.792 kDa.
Cite This Product
StressMarq Biosciences Cat# SPC-946, RRID: AB_2707427
Certificate of Analysis
A 1:250 dilution of SPC-946 was sufficient for detection of CDK9 (pSer347) in 10 µg of HeLa cell lysate by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.
Biological Description
Alternative Names
C-2K Antibody, CDC2 related kinase Antibody, CDC2L4 Antibody, CDK9_HUMAN Antibody, Cell division cycle 2-like protein kinase 4 Antibody, Cell division protein kinase 9 Antibody, CTK1 Antibody, Cyclin dependent kinase 9 Antibody, PITALRE Antibody, Serine/threonine-protein kinase PITALRE Antibody, TAK Antibody, Tat associated kinase complex catalytic subunit Antibody
Research Areas
Cancer, Cell Cycle, Cell Signaling, Epigenetics and Nuclear Signaling, Immunology
Cellular Localization
Nucleus
Accession Number
NP_001252
Gene ID
1025
Swiss Prot
P50750
Scientific Background
CDK9 (also designated PITALRE) has been shown to specifically phosphorylate the retinoblastoma protein. The more recently cloned Drosophila protein, P-TEFb, is thought to be the homolog of mammalian PITALRE. P-TEFb has been shown to be required for HIV Tat transcriptional activation.
Product Images
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Product Citations (0)
Currently there are no citations for this product.StreptavidinProperties:Homo-tetrameric protein purified from Streptomyces avidinii which binds four biotin molecules with extremely high affinityMolecular weight: 53 kDaFormula: C10H16N2O3SApplications: Western blot, immunohistochemistry, and ELISAStreptavidin Datasheet
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究,同时在其他领域也取得了一定成就,包括翻译后修饰,提供甲基化与乙酰基化抗体。其中,细胞应激领域主要包括热休克蛋白(HSP)领域。我们公司不仅在热休克蛋白领域领先全球,而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列,分别涉及抗体、蛋白、酶联免疫吸附试验(ELISA)试剂盒及小分子领域。
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