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StressMarq/Anti-GRK2 Antibody (pTyr356)/SPC-922D-STR/100-µl

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Overview: Product Name GRK2 Antibody (pTyr356) DescriptionRabbit Anti-Human GRK2 (pTyr356) Polyclonal Species Reactivity Human Applications WB, AM Antibody Dilution WB (1:250); optimal dilutions for assays should be determined by the user. Host Species Rabbit Immunogen Species Human Immunogen A phospho-specific peptide corresponding to residues surrounding Tyr356 of human GRK2 (AA353-359) Conjugates Alkaline Phosphatase, APC, ATTO 390, ATTO 488, ATTO 565, ATTO 594, ATTO 633, ATTO 655, ATTO 680, ATTO 700, Biotin, FITC, HRP, PE/ATTO 594, PerCP, RPE, Streptavidin, Unconjugated Properties Storage Buffer PBS pH7.4, 50% glycerol, 0.025% Thimerosal Storage Temperature -20ºC Shipping Temperature Blue Ice or 4ºC Purification Peptide Affinity Purified Clonality Polyclonal Specificity Detects 79.574 kDa. Cite This Product StressMarq Biosciences Cat# SPC-922, RRID: AB_2706995 Certificate of Analysis A 1:250 dilution of SPC-922 was sufficient for detection of GRK2 (pTyr356) in 10 µg of human colon cancer cell lysate by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody. Biological Description Alternative Names ADRBK1 Antibody, Adrenergic beta receptor kinase 1 Antibody, ARBK1_HUMAN Antibody, BARK Antibody, BARK1 Antibody, Beta adrenergic receptor kinase 1 Antibody, Beta ARK 1 Antibody, G protein coupled receptor kinase 2 Antibody Research Areas Cell Signaling, Neuroscience, Neurotransmitter Receptors Cellular Localization Cytoplasm, Cell membrane Accession Number NP_001610 Gene ID 156 Swiss Prot P25098 Scientific Background G protein-coupled receptor kinases (GRKs) belong to a class of enzymes that regulate signal transduction. At least seven members of the GRK family have been identified. These include rhodopsin kinase (GRK 1), two forms of beta-adrenergic receptor kinase: GRK 2 (betaARK, betaARK1) and GRK 3 (betaARK2), IT-11 (GRK 4), GRK 5, GRK 6 and GRK 7. Phosphorylation of receptors by GRKs appears to be strictly dependent on the receptor being in its agonist-activated state. Product Images Currently there are no images for this product Product Citations (0) Currently there are no citations for this product.StreptavidinProperties:Homo-tetrameric protein purified from Streptomyces avidinii which binds four biotin molecules with extremely high affinityMolecular weight: 53 kDaFormula: C10H16N2O3SApplications: Western blot, immunohistochemistry, and ELISAStreptavidin Datasheet

StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。