首页 > StressMarq > StressMarq/Anti-Ki67 Antibody/SPC-1327D-A700/100-µl

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StressMarq/Anti-Ki67 Antibody/SPC-1327D-A700/100-µl

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SPC-1327D-A700

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Overview:ProductNameKi67AntibodyDescriptionRabbitAnti-HumanKi67PolyclonalSpeciesReactivityHumanApplicationsIHC,ICC/IF,ELISAAntibodyDilutionIHC(1:100),ICC/IF(1:500),ELISA(1:20000);optimaldilutionsforassaysshouldbedeterminedbytheuser.HostSpeciesRabbitImmunogenSpeciesHumanImmunogenSynthesizedpeptidederivedfromC-terminalofhumanki67.ConjugatesAlkalinePhosphatase,APC,ATTO390,ATTO488,ATTO565,ATTO594,ATTO633,ATTO655,ATTO680,ATTO700,Biotin,FITC,HRP,PE/ATTO594,PerCP,RPE,Streptavidin,UnconjugatedPropertiesStorageBufferPBSpH7.4,50%glycerol,150mMNaCl,0.02%sodiumazideStorageTemperature-20ºCShippingTemperatureBlueIceor4ºCPurificationAffinityPurifiedClonalityPolyclonalIsotypeIgGSpecificityDetectsendogenouslevelsoftotalki67protein.CiteThisProductStressMarqBiosciencesCat#SPC-1327,RRID:AB_2713673CertificateofAnalysisA1:100dilutionofSPC-1327wassufficientfordetectionofKi67inhumanlungcarcinoatissueusingGoatAnti-RabbitIgGasthesecondaryantibody.BIOLOGicalDescriptionAlternativeNamesAntigenidentifiedbymonoclonalantibodyKi67antibody,AntigenKI-67antibody,AntigenKI67antibody,KI67_HUMANantibody,KIAantibody,MarkerofproliferationKi-67antibody,MIB1antibody,MIBantibody,MKI67antibody,PPP1R105antibody,ProliferationrelatedKi67antigenantibody,Proteinphosphatase1regulatorysubunit105antibody,RP11-380J17.2antibodyCellularLocalizationChromosome,NucleusAccessionNumberNP_002408.3GeneID4288SwissProtP46013ScientificBackgroundAntigenKI-67alsoknownasKi-67orMKI67isaproteinthatinhumansisencodedbytheMKI67gene.AntigenKI-67isanuclearproteinthatisassociatedwithandmaybenecessaryforcellularproliferation.FurThermore,itisassociatedwithribosomalRNAtranscription.InactivationofantigenKI-67leadstoinhibitionofribosomalRNAsynthesis.Duetoitsassociationwithcelldivisonprocess,Ki-67isroutinelyusedascellularproliferationmarkerofsolidtumorsaswellascertainhematologicalmalignancies,andacorrelationhasbeendemonstratedbetweenKi-67indexandthehistopathologicalgradeofcancers.References1.SchonkDM.etal.(1989)Hum.Genet.83(3):297–9.2.BullwinkelJ.etal.(2006)J.Cell.Physiol.206(3):624–35.3.RahmanzadehR.etal.(2007)CellProlif.40(3):422–30.4.ScholzenTandGerdesJ(2000)J.Cell.Physiol.182(3):311–22.ProductImagesImmunohistochemistryanalysisusingRabbitAnti-Ki67PolyclonalAntibody(SPC-1327).Tissue:LungCarcinomaTissue.Species:Human.Fixation:Formalinfixedparaffin-embedded.PrimaryAntibody:RabbitAnti-Ki67PolyclonalAntibody(SPC-1327)at1:100.Theimageontherightistreatedwiththesynthesizedpeptide.Immunocytochemistry/ImmunofluorescenceanalysisusingRabbitAnti-Ki67PolyclonalAntibody(SPC-1327).Tissue:Cos7.Species:Monkey.PrimaryAntibody:RabbitAnti-Ki67PolyclonalAntibody(SPC-1327)at1:100.Theimageontherightistreatedwiththesynthesizedpeptide.ProductCitations(0)Currentlytherearenocitationsforthisproduct. ATTO700Overview:HighfluorescenceyieldExcellentthermalandphotostABIlityQuenchedbyelectrondonorsVeryhydrophilicGoodsolubilityinpolarsolventsZwitterionicdyeMolarMass:575g/molATTO700Datasheet OpticalProperties:λex =700 nmλem=719nmεmax=1.25×105Φf= 0.25τfl =1.6nsBrightness= 31.3Laser =676nmFilterset =Cy®5.5

StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。