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bioporto/Anti-Surfactant protein D (human, hSP-D)/1kit/HYB 245-01

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Cat. No.HYB 245-01SpecificityHYB 245-01 is specific for human SP-D.ImmunogenRecombinant neck CRD SP-DHostMousePositive Species ReactivityHumanNegative Species ReactivityNot determinedIsotypeIgG1/kGene ID6441Clone Number12G5Epitope SpecificityNot determinedUnit Size200 µL: Cat. No. HYB 245-01-021 mL: Cat. No. HYB 245-01-11 mg/mL +/- 15%. See Certificate of Analysis for details.PurificationProtein A/G purified (from culture supernatant)FormLiquidSolvent0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azideConjugationUnconjugated BSA freeStorage4-8ºC without exposure to light. No precautions necessary during handling.TargetSurfactant protein D (SP-D) is synthesized and secreted by lung epithelial cells. It belongs to group III ofthe family of C-type lectins and members of this group has overall structure consisting of multipleglobular "head" regions linked by triple-helical, collagen-like, strands. This group also includes SP-A andthe serum proteins mannan-binding protein, conglutinin and collectin-43, all of which have been shownto bind to the C1q receptor found on a wide variety of cells. Both SP-D and SP-A have been shown toenhance oxygen radical production by alveolar macrophages. The serum concentration is 88 ng/ml inhealthy individuals. (1)

丹麦Bioporto公司成立于2000年，致力于开发抗体产品及诊断试剂盒。2005年首次开发出NGAL ELISA 试剂盒，该产品于2006年获得欧盟CE认证，可用于急性肾功能损伤的临床诊断和监测。其目标是开发出更多的临床诊断专利产品。