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Nordicmubio/OGR1/GPR68/X1601C

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OGR1/GPR68Catalogue number: X1601CProduct Type Control LysateUnits100 µl Species reactivity HumanApplication Western Blotting BackgroundOGR1 (originally identified as GPR68) is a high-affinity receptor for sphingosylphosphorylcholine (SPC).SPC is a member of a class of bioactive lipids which regulate cellular functions.These functions include cell proliferation and growth inhibition, smooth muscle contration and wound healing.SPC also stimulated signalling pathways that induce tyrosine phosphorylation, activate MAP kinases and protein kinase C, modify ion channel activity and increase intracellular Ca2+ concentration.OGR1 is expressed in placenta, lung, liver, spleen, testis, small intestine and peripheral blood leukocytes.It is not found in thymus, ovary, colon, skeletal muscle, kidney or pancreas. Product Product Form: Unconjugated Formulation: Provided in 10% glycerol, 0.063 M Tris-HCl (pH 6.8), 2% SDS and 0.002% bromophenol blue, 5% 2-mercaptoethanolConcentration: See vial for concentration ApplicationsFor use as a positive control with Exalpha's OGR1 polyclonal antibody (Cat. No. X1600P) for Western blot analysis.Functional Analysis: Western Blotting StorageProduct should be stored at -20ºC. Aliquot to avoid freeze/thaw cycles Product Stability: Products are stable for one year from purchase when stored properly Shipping Conditions: Ship at ambient temperature, freeze upon arrival CautionThis product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. It may contain hazardous ingredients. Please refer to the Safety Data Sheets (SDS) for additional information and proper handling procedures. Dispose product remainders according to local regulations.This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information. References1. Xu, Y., et al. 'Sphingosylphosphorylcholine is a ligand for ovarian cancer G-protein-coupled receptor 1.' Nature Cell Biol. 2000: 2, 261-267 Safety Datasheet(s) for this product:NM_Glycerol/wp-content/uploads/SDS/SDS Antibodies with glycerol Nordic-MUbio.pdf

Noridic-Mubio是荷兰的一家著名的免疫学试剂生产厂商，因收购An Der Grub Bio Research GmbH(ADG)，增加了自己的产品线：全球最好的固定破膜剂FIX&PERM 。Nordic-Mubio严格遵照ISO9001标准生产高质量的抗体，主要为针对细胞粘附蛋白、核蛋白和骨架蛋白的抗体。同时Nordic-Mubio也是斑马鱼抗体开发的引领者之一，拥有50多种可用于斑马鱼免疫荧光检测的抗体。