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Peptides/Peptides International/1000µg/HOR-275-1000µg
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Product Code: HOR-275Synonyms/Product Alternate Names: Thymosin β4, Thymosin b-4, Thymosin beta-4, T beta 4, Fx , TB4X, PTMB4, TMSB4, TB500, TB-500, Ac-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys-Glu-Thr-Ile-Glu-Gln-Glu-Lys-Gln-Ala-Gly-Glu-Ser-OHIntroduction: CB1 cannabinoid receptor-interacting protein 1 (CNRIP1) is a 164 amino acid protein and G-protein coupled receptor which is a member of the CNRIP family. The CNRIP1 interacts with the C-terminal tail of cannabinoid receptor 1. CNRIP1 is expressed in the brain tissue and, at low levels, in the testis. CNRIP1 is involved in appetite, synaptic plasticity, neuroprotection and analgesia.Description: Thymosin b4 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 43 amino acids and having a molecular mass of 4.9kDa.The Thymosin b4 Human is purified by proprietary chromatographic techniques.Physical Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.Formulation: Lyophilized from a 0.2um filtered concentrated solution in 1xPBS, pH 7.4.Solubility: It is recommended to reconstitute the lyophilized Thymosin B4 in sterile 18M-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.Stability: Lyophilized Thymosin B4 Human although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Thymosin B4 Human should be stored at 4°C between 2-7 days and for future use below -18°C. Please prevent freeze-thaw cycles.Purity: Greater than 95.0% as determined by SDS-PAGE and HPLC analyses.For LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.Storage Conditions: -20 °CPurity: >98.0% as determined by RP-HPLC.Molecular Weight: 4963.55 DaMolecular Formula: C212H350N56O78SOne-Letter Code:Ac-SDKPDMAEIEKFDKSKLKKTETQEKNPLPSKETIEQEKQAGES-OH http://www.fasebj.org/content/25/3/907.full.pdf+htmlDelivery Details: All quantities are subject to availability. Please allow 7-10 days for delivery.Custom QuoteBulk Qty Request FormView All Recombinant ProteinsPeptides International Certified To ISO 9001:2015© 2020 Peptides International. All rights reserved.Sitemap Site Info Contact Links NewsADS/CofAOOHnado_blizzardCreated with Sketch.
现代营养学研究发现:人类摄食蛋白质经消化道的酶作用后,大多是以低肽形式消化吸收的,以游离氨基酸形式吸收的 比例很小。进一步的试验又揭示了肽比游离氨基酸消化更快、吸收更多,表明肽的生物效价和营养价值比游离氨基酸更高。这也正是活性肽的无穷魅力所在。
生物活性肽(Bioact ive Peptide s ,BA P)就是对生物机体的生命活动有益或是具有生理作用的肽类化合物, 是一类相对分子质量小于6000Da , 具有多种生物学功能的多肽。其分子结构复杂程度不一,是介于氨基酸与蛋白质之间的分子聚合物,小至由两个氨基酸组成,大至由数十个氨基酸通过肽键连接而成,而且这些多肽可通过磷酸化、糖基化或酰基化而被修饰 [1]  。
生物活性肽有多种多样的生理功能, 如激素作用、免疫调节、抗血栓、抗高血压、降胆固醇、抑菌、抗病毒、抗癌作用等 [2]  。这些功能是原蛋白质或组成氨基酸所不具备的独特的生理机能, 且许多活性肽的组成氨基酸并不一定是必需氨基酸,这就为利用蛋白质资源, 特别是那些原本认为生物效价不高的蛋白质资源利用提供了新的机遇,是当前国际食品界最热门的研究课题和极具发展前景的功能因子。20世纪末,科学家在破解基因的秘密的同时,也对存在于生物体内的另一类奇妙物质的研究发生极大的兴趣。这类物质就是生物活性,或称功能肽,由氨基酸组成,是一种小分子的蛋白质,比如胰岛素,就是一种多肽,再如在日本应用广泛的促进钙吸收的CCP,在欧美风靡一时的促进生长的HGH……。
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