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Echelon/d5-D-myo-Phosphatidylinositol 3,4,5-trisphosphate DiC16/1 mg/P-3916d
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产品说明
Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 3,4,5-trisphosphate (PIP3), formed from PI(4,5)P2 though phosphorylation by PI 3-kinase, activates numerous signaling pathways resulting in cell proliferation, growth, survival, glucose transport and protein synthesis. High PIP3 levels from dysregulation of PI3-K have been demonstrated in cancer and inflammatory diseases. PIP3 is hydrolyzed by the phosphatases PTEN to PI(4,5)P2 and SHIP to PI(3,4)P2. This analog is deuterated at the glycerol.FilterDeuterated Lipids, Phosphoinositides, PI(3,4,5)P3CategoriesLipidsMolecular FormulaC41H73D5Na4O22P4Molecular Weight (g/mol)1143.94Purity95%Storage-20 °C or below

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