首页 > Echelon > Echelon/PI(3,4,5)P3 18:0/20:4/1 mg/P-3924

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Echelon/PI(3,4,5)P3 18:0/20:4/1 mg/P-3924

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P-3924

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产品说明

PI(3,4,5)P3 (Phosphatidylinositol 3,4,5-trisphosphate) 18:0/20:4 is a synthetic, purified PI(3,4,5)P3 with stearoyl and arachidonoyl acyl groups.Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 3,4,5-trisphosphate (PIP3), formed from PI(4,5)P2 though phosphorylation by PI 3-kinase, activates numerous signaling pathways resulting in cell proliferation, growth, survival, glucose transport and protein synthesis. High PIP3 levels from disregulation of PI3-K have been demonstrated in cancer and inflammatory diseases. PIP3 is hydrolyzed by the phosphatases PTEN to PI(4,5)P2 and SHIP to PI(3,4)P2.Product Keywords: 1-Stearoyl-2-arachidonoyl-phosphatidylinositol 3,4,5-trisphosphate, PtdIns(3,4,5)P3 (18:0/20:4), PI(3,4,5)P3 (18:0/20:4), or PIP3Bulk discounts available, please email echelon@echelon-inc.com for information.Publications Powered by Bioz See more details on BiozCategoriesLipidsFilterPhosphoinositides, PI(3,4,5)P3CAS Number799268-60-3Molecular FormulaC47H82Na4O22P4Molecular Weight (g/mol)1,214.99Purity>95%Storage-20 °C or below

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