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echelon-inc/BODIPY® FL Phosphatidylinositol 3-phosphate/100ug/C-03F6-100ug
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产品说明
 CatalogNo.: C-03F6MW: 1231.19Description: WatersolubleanalogofPI(3)Plabeledwiththegreenfluorophore,Bodipy®-FLatthesn-1position.Phosphoinositides(PIPns)areminorcomponentsofcellularmembranesbutareintegralsignalingmoleculesforcellularcommunication.Phosphatidylinositol3-phosphateisenrichedinearlyendosomeshavingrolesinendosomefusionandreceptorsortingandinternalizationinmultivesicularbodies.PI(3)PhasalsobeenfoundattheplasmamembraneandisinvolvedinthetranslocationoftheglucosetransportproteinGLUT4.Excitation/Emission503/513nmStorage-20°CFeaturedinPublications:1)Caromile,L.A.,A.Oganesian,etal.(2010)."Theneurosecretoryvesicleproteinphogrinfunctionsasaphosphatidylinositolphosphatasetoregulateinsulinsecretion."JBiolChem285(14):10487-96.2)Rudge,S.A.,D.M.Anderson,etal.(2004)."Vacuolesizecontrol:regulationofPtdIns(3,5)P2levelsbythevacuole-associatedVac14-Fig4complex,aPtdIns(3,5)P2-specificphosphatase."MolBiolCell15(1):24-36.3)Oganesian,A.,M.Poot,etal.(2003)."ProteintyrosinephosphataseRQisaphosphatidylinositolphosphatasethatcanregulatecellsurvivalandproliferation."ProcNatlAcadSciUSA100(13):7563-8.

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