首页 > Echelon > Echelon/BODIPY TMR PI(4,5)P2/100 ug/C-45M6

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Echelon/BODIPY TMR PI(4,5)P2/100 ug/C-45M6

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C-45M6

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产品说明

BODIPY TMR PI(4,5)P2 (BODIPY TMR Phosphatidylinositol 4,5-bisphosphate) is a water soluble analog of PI(4,5)P2 (PIP2) labeled with the orange fluorophore, Bodipy®-TMR, at the sn-1 position.Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 4,5-bisphosphate (PIP2) has been shown to play a central role in a variety of cellular functions. Amongst its many functions, PIP2 is a substrate for Phospholipase C-coupled G-protein pathways involved in intracellular calcium release in a number of tissues. It is also a substrate for class I phosphoinositide 3-kinase (PI3-K) forming PI(3,4,5)P3.Excitation/Emission542/574 nmStorage-20 °C, protect from lightPublications Powered by Bioz See more details on Bioz1) Cabanos C, Wang M, Han X, Hansen SB (2017) A Soluble Fluorescent Binding Assay Reveals PIP2 Antagonism of TREK-1 Channels. Cell Rep 20(6):1287–1294Bulk discounts available, please email echelon@echelon-inc.com for information.CategoriesLipidsFilterFluorescent, Phosphoinositides, PI(4,5)P2Excitation/Emission542/574 nmMolecular FormulaC78H147BF2N9O22P3Molecular Weight (g/mol)1,704.78Purity>95%Storage-20 °C or below, protect from light

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