产品说明
Isoprenoid compounds are a diverse group of natural products which are essential components in all cells. Isoprenoids are biosynthesized from the simple precursors isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Eukaryotes, fungi, and some gram-positive bacteria produce IPP through the mevalonate (MVA) pathway whereas gram-negative and some gram-positive bacteria utilize the non-mevalonate or 2-C-methyl-D-erythritol-4-phosphate (MEP) pathway. 2-C-Methyl-D-erythritol 2,4-cyclophosphate (cMEPP) is an intermediate in the non-mevalonate pathway. It is formed by from MECDP Synthase from CDP-MEP and converted to 1-hydroxy-2-methyl-2-buten-4-yl diphosphate (HDMAPP) by IspG (GcpE).Featured in Publications1) Xiao, Y., T. Savchenko, et al. (2012). “Retrograde Signaling by the Plastidial Metabolite MEcPP Regulates Expression of Nuclear Stress-Response Genes.” Cell 149(7): 1525.2) Zhou, K., R. Zou, et al. (2012). “Metabolite Profiling Identified Methylerythritol Cyclodiphosphate Efflux as a Limiting Step in Microbial Isoprenoid Production.” PLoS ONE 7(11): e47513.3) Hsiao, C.-H. C. and A. J. Wiemer (2018). “A power law function describes the time- and dose-dependency of Vγ9Vδ2 T cell activation by phosphoantigens.” Biochem Pharmacol 158: 298-304.4) Ma, Y., et al. (2019). “Metabolic Engineering of the MEP Pathway in Bacillus subtilis for Increased Biosynthesis of Menaquinone-7.” ACS Synthetic Biology 8(7): 1620-1630.Bulk discounts available, please email echelon@echelon-inc.com for information.Alternate Names: cMEPP, MEcPPCategoriesBiochemical ReagentsFilterMEP PathwayCAS Number151435-51-7Molecular FormulaC5H12O8P2Molecular Weight (g/mol)C5H12O8P2Purity>90%Storage-20 °C or below
Echelon产品线
★合成磷脂、磷酸肌醇、鞘脂及其衍生物 |
★脂蛋白质相互作用工具 |
★脂质含量检测试剂盒 ★脂质相关生物酶活性检测,抑制剂筛选试剂盒 |
新品排行榜
1
Echelon/High Throughput Autotaxi...
2
Echelon/Tks5 VHH Antibody/250 ug...
3
Echelon/d5-D-myo-Phosphatidylino...
4
Echelon/Tensin 4 VHH Antibody/25...
5
Echelon/Autotaxin Inhibitor Scre...
6
Echelon/PTEN Activity ELISA Kit/...
7
Echelon/Hyaluronidase Activity E...
8
Echelon/Vinculin VHH Antibody/25...
9
Echelon/Vac14 Antibody, polyclon...
10
Echelon/Autotaxin Activity Assay...
文章排行榜
1
Echelon-inc
2
Echelon-inc
3
eBioscience AccutaseTM细胞分离溶液
4
eBioscience-莱兹生物免疫学技术讲座圆满落幕!
5
Echelon Bioscience公司简介,优势订购!
6
使用eBioscience流式抗体的常见问题
7
Echelon Biosciences 宣布与 ProBioscience Technologies 合作在东南亚分销 - Echelon Biosciences,Ebioscience 现货
8
FierceBiotech:2014年最热门的15家生物公司
9
Echelon Biosciences Incorporated中国采购 Echelon脂质含量检测试剂盒
10
Echelon经销商/代理商 Echelon抑制剂筛选试剂盒