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yesbiotech/mAb anti-Human GP IIb/IIIa, 291/0.1 mg/MO-M40040J

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DescriptionAdditionalDescription DetailsDescription:Mouse monoclonal antibody to human platelet membrane glycoprotein IIb/IIIa (GP IIb/IIIa)Purification:Protein G affinity purifiedProduct Type: Primary antibodyTarget Protein:Human platelet membrane glycoprotein IIb/IIIaImmunogen:Human platelet suspensionFusion Myeloma:Sp2/0-Ag14Specificity:The mAb reacts with human platelet.Species Reacitvity:Human, others not testedHost / Isotype:Mouse, IgG2b KappaFormulation:Lyophilized from a solution in 0.01M PBS, pH 7.2Reconstitution:Double distilled water is recommended to adjust the final concentration to 1.00mg/mL.Storage: Store at -20oCResearch Area:Hematology, blood coagulationBackground:Human platelet membrane glycoprotein Glycoprotein IIb/IIIa (GP IIb/IIIa) is a dominate receptor on the platelet membrane with very high molecular weight (>200kDa). After the platelet is activated, the GP IIb/IIIa receptor complex changes conformation and binds to fibrinogen in blood circulation with high affinity. The activation of platelets is initiated locally when the endothelial layer is wounded and the platelets are exposed to the collagen underneath the endothelium. The fibrinogen aggregates with platelets when binding to the GP IIb/IIIa receptor on platelets, thus primary haemostasis (Platelet clot) is formed.Application:ELISA:The mAb is reactive to platelet coated ELISA plate.Other applications have not been evaluated.References:If research is published using this product, please inform Anogen in order to cite the reference on this datasheet. Anogen will provide one unit of product in the same category as gratitude. Additional Additional InformationProduct SpecificitymAb anti-Human GP IIb/IIIa, 291ApplicationEIASize0.1 mg

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