IHC-TekAFP IHC AntibodyRRP:$258.00 SKU:IW-MA1001Condition:Weight:Availability:Shipping:Minimum Purchase: unit(s)Maximum Purchase: unit(s):Gift Wrapping:Quantity:123456789101112131415161718192021222324252627282930Buy in bulk and saveProduct DescriptionDescriptionAlpha-fetoprotein (AFP) is a major plasma protein in the fetus, where it is produced by the yolk sac and liver. Direct confirmation of the assignment of the AFP gene to chromosome 4 by in situ hybridization was provided by Harper and Dugaiczyk (1983), who placed the gene in the q11-q22 region, the same region as the albumin gene. Structure and evolution of human alpha-fetoprotein deduced from partial sequence of cloned cDNA.As the major fetal serum protein, Alpha-fetoprotein is not essential for embryonic development but is required for female fertility.Catalog NumberIW-MA1001Quantity9 mlHostMouseCloneAP-1IsotypeMouse IgG2aImmunogenHuman α-fetoproteinPurityPurified by the goat anti-mouse IgG affinity chromatographyConjugateUnconjugatedSpecies ReactivityHuman, mouse, rat. Not tested in other species.Positive ControlLiverCellular LocalizationCytoplasmicFormReady to use solution in PBS with stabilizer and 0.01% sodium azide. No further dilution needed. Serum blocking step should be omitted.StorageStore at 2-8 °C. Do not freeze.ApplicationsIHC-P: Heat induced epitope retrieval is required on formalin fixed paraffin sections. IHC-Fr: Not tested.ICC: Not tested.LimitationsThis product is intended for Research Use Only. Interpretation of the test results is solely the responsibility of the user.PrecautionsUsers should follow general laboratory precautions when handling this product. Wear personal protective equipment to avoid contact with skin and eyes.References1. D"Eustachio, P.; Ingram, R. S.; Tilghman, S. M.; Ruddle, F. H. : Murine alpha-fetoprotein and albumin: two evolutionarily linked proteins encoded on the same mouse chromosome. Somat. Cell Genet. 7: 289-294, 1981. 2. Beattie, W. G.; Dugaiczyk, A. : Structure and evolution of human alpha-fetoprotein deduced from partial sequence of cloned cDNA. Gene 20: 415-422, 1982. 3. Gabant, P.; Forrester, L.; Nichols, J.; Van Reeth, T.; De Mees, C.; Pajack, B.; Watt, A.; Smitz, J.; Alexandre, H.; Szpirer, C.; Szpirer, J. : Alpha-fetoprotein, the major fetal serum protein, is not essential for embryonic development but is required for female fertility. Proc. Nat. Acad. Sci. 99: 12865-12870, 2002. Find Similar Products by CategoryIHC AntibodiesProduct ReviewsWrite Your Own ReviewHow do you rate this product?5 stars (best)4 stars3 stars (average)2 stars1 star (worst)Write a headline for your review here:Write your review here:Your email:We promise to never spam you, and just use your email address to identify you as a valid customer.Enter your name: (optional)Enter the code below:This product hasn"t received any reviews yet. Be the first to review this product!Write review