生物芯片国际所有大公司地址及简介http://www.Affymetrix.com/http://www.gsilumonics.com/http://imaging.brocku.ca/FrameSet1.htmlhttp://www.probes.com/http://arrayit.com/biochip4/http://www.gatconsortium.org/http://www.spotfire.com/of_2_0.htmhttp://www.genomesystems.com/http://www.biorobotics.com/http://www.cartesiantech.com/http://www.ias.com/http://www.biodot.com/index.htmhttp://www.genemachines.com/index.htmlhttp://www.biodiscovery.com/http://www.xeno.com/http://www.cellrobotics.com/http://www.ultranet.com/~rADIus/http://www.incyte.com/about/management.htmlhttp://www.packardinstrument.com/prod_serv/biochiparrayer.htmhttp://www.sigenetics.com/http://www.genetix.co.uk/Instruments.htmhttp://www.esit.com/ArrayorSlideCompanieshttp://www.superarray.com/http://www.ultranet.com/~radius/http://www.resgen.com/http://www.scimatrix.com/http://www.mergen-ltd.com/http://dnamicroarray.com/http://arrayit.com/http://www.clontech.com/(soon)http://www.operon.com/ss2b1/home.htmlhttp://www.phase1tox.com/http://www.nenLifesci.com/http://www.genomesystems.com/http://www.displaysystems.com/http://www.s-and-s.com/index.htmhttp://www.biochip.com/tech_uk.htmlhttp://www.cmt.corning.com/http://www.SurModics.com/http://www.gracebio.com/简介ACLARABioSciences,Inc.,(usedtobecalledSoaneBiosciences)Hayward,California(Plasticchipsandmicrofluidicsystemsbasedon"Lab-On-A-Chip"microfluidicsUSPatent5,750,015:"Methodanddeviceformovingmoleculesbytheapplicationofapluralityofelectricalfields")WinsNISTATPAwardin"ToolsforDNADiagnostics"forProject:MultiplexedSamplePreparationMicrosystemforDNADiagnosticsAffymetrix,Inc.,SantaClara,California(Thetechnologyleader;manufacturesthewidelyusedGeneChip®arrays,includingHIV,p450,p53,RatToxicologyU34arrays,etc.)AlexionPharmaceuticalsInc.,NewHaven,ConnecticutAlphaGene,Inc.,Woburn,Massachusetts(fulllengthCDNAFLEX?andMicroFLEXlibraryconstruction;HighThroughputGeneExpressionProfiling;HighThroughputDNASequencing;Bioinformatics)AppliedPrecision,Inc.,ssaquah,Washington.ArrayWoRxisawidefieldlightsourcebasedmicroarrayscanner,combineslimitlesswavelengthpossibiliteswithautomationandimageprocessingsoftware.ArrayIt,MakingDNAchip.AxonInstruments,Inc.,FosterCity,California(GenePix4000IntegratedMicroarrayScannerandAnalysisSoftware,simultaneouslyscansmicroarrayslidesattwowavelengthsusingaduallaserscanningsystem,displaysimagesfromtwowavelengthsandaratioimageastheyareacquiredinrealtime;US$50,000)AxySPharmaceuticals,LaJolla,California:WinsNISTATPAwardin"ToolsforDNADiagnostics"Project:LiquidArrayTechnologyDevelopmentBioChipTechnologiesbioDevicePartners,Cohasset,MA.ProvidesconsultingservicestothemicorarrayingcommunityintheareaofopticsandinstrumentationBioDiscovery,Inc.,LosAngeles,California(ImaGene?,specialimageprocessinganddataextractionsoftware)BiomedicalPhotometrics,Inc.,(MACROscope?forreadinggeneticmicroarrays,incollaborationwithCanadianGeneticMicroarrayConsortium)bioMerieux,invitrodiagnosticsBioRoboticsLtd.,Comberton,Cambridge,UK(MicroGrid,forarrayingoligonucleotidesorcDNAclonesonglassslidesandplasticchips)Brax,Cambridge,UKCadusPharmaceuticalCorp.,Tarrytown,NewYork(yeastlivingchip)CaliperTechnologiesCorp.,PaloAlto,California:LabChips?basedonmicrofluidics.Awarded$2millioncontractbyNISTtodevelophigh-throughputDNAdiagnosticplatform.Project:ReferenceLaboratoryLabChip?DNADiagnosticsSystemCartesianTechnologies,Inc.,Irvine,CA.PixSysPASeries:forAutomatedliquidhandlingsystemforcreatinghigh-densityarraysforgenomicsresearch.ScanArray3000:AFluorescentImagingSystemformicroarraybiochips.Celera,Rockville,MarylandCellomics,Inc.,Pittsburgh,Pennsylvania(ArrayScan?,cell-based"HighContentScreening"(HCS)fordrugdiscovery)CepheidSunnyvale,California(microfluidics)CiphergenBiosystems,PaloAlto,California.ProteinChip?Arraysfortheinvestigationofproteinsonthefemtomolescaledirectlyfromtheir"native"environments.BasedonSurface-EnhancedLaserDesorption/Ionization(SELDI?).ClinicalMicroSensors,Inc.,Pasadena,California:DNAmicrochip-basedmedicaldiagnostics;detectionofdirectlydetectDNAviaelectrontransfer.WinsNISTATPAwardin"ToolsforDNADiagnostics"Project:DNADiagnosticsforthePointofCareUsingElectronicNucleicAcidDetectionClontechCorningScienceProductsDivision,Acton,MAprovidesthe(CorningMicroarrayTechnology)CMT-GAPSaminosilanecoatedslidesandCMT-Hybridizationchamber.CorvasInternational,Inc.,(2Dgel,proteomics)CuraGenCorp.,NewHaven,Connecticut.GeneCalling?andQuantitativeExpressionAnalysis(QEA?),CuraMode,CuraToxdiaDexus,LLC,SantaClara,California.jointventurebetweenSmithKlineBeechamCorp.andIncytePharmaceuticals,Inc..SpecializedinusingmicroarraytechnologyformoleculardiagnosticsDNAmicroarray.com.offerscomplete"madetoorder"highdensityDNAmicroarraysynthesisandanalysissservices.Prices,availABIlity,andturnaroundtimeseemimpressive.GelbiochipGeneLogic,Inc.,Columbia,Maryland(Flow-thruChipTM:hashundredsofthousandsofdiscretemicroscopicchannelsthatpasscompletelythroughit.Probemoleculesareattachedtotheinnersurfaceofthesechannels,andtargetmoleculesflowthroughthechannels,comingintocloseproximitytotheprobes.Thisproximityfacilitateshybridization.READS?,RestrictionEnzymeAnalysisofDifferentially-expressedSequences,forcapturingandanalyzingtheoverallgeneexpressionprofileofagivencellortissuetypetoidentifydrugtargets)GeneDataAG(Basel,Switzerland),analysisofgenomicsandproteomicsdata:GeneDataWorkBench,GeneDataExpressionist.GenemachinesGenomicInstrumentationServices,Inc.,MenloPark,California(OmniGrid,glassslidesornylonmembranes,similartoDr.PatBrown"s)GeneralScanningInc.,Watertown,Massachusetts(laserscanningandmicropositioning,manufacturesMicroArrayBiochipScanningSystem:ScanArrayTM).NowcalledGSILumonicsGeneScreen,Inc.,TheGeneticsProfilingCompanyGeneTraceSystemsGeneticAnalysisTechnologyConsortium(GATC)GeneticMicroSystemsInc.,Woburn,Massachusetts(instrumentationforDNAmicroarray-basedanalysis)GenetixLtd.,Christchurch,Dorset,UK(Q-Bot,Q-Pix)GenomeSystemsInc.,St.Louis,MO,awhollyownedsubsidiaryofIncytePharmaceuticals,Inc.,GDA:GeneDiscoveryArrayGenometrixInc.,TheWoodlands,Texas(Bioscanner?,GeneView®,UniversalArrays?,Risk-Tox)GenomicSolutions,AnnArbor,Michigan(Flexys?modularroboticsystem,GeneTAC?andGenomicIntegrator?arrayanalysisproductsautomatestheimagingandanalysisofgenemicroarrays.)GenosysBiotechnologies,Inc.,TheWoodlands,Texas(Panorama?E.coliGeneArrays,4,290genesperarray)GENSET,Paris,France(specializedinpharmacogenomics)GenzymeMolecularOncology(SAGE®:SerialAnalysisofGeneExpression)HPGeneArrayScanner(usedbyAffymetrixandothers)HyseqInc.,Sunnyvale,California(SequencingByHybridization.HyXplatformandGeneDiscovery,HyGnostics,andHyChip?modules)Illumina,Inc.,SanDiego,California.utilizesfiberoptics,microfabrication,andadvancedinformationprocessingtocreatearrayswhere250,000discretesensorsfitonaprobethediameteroftheheadofapin.I.M.A.G.E.Consortium:"Sharingresourcestoachieveacommongoal-thediscoveryofallgenes"ImagingResearch,Inc.,St.Catharines,Ontario,Canada.Thecompanywritessoftware,developsdetectiontechnologies,andintegratessystemsforimageanalysis.ItsPC-basedArrayVisionTMsystemhasbeenwidelyusedforrapidandautomatedanalysisofgenomearrays.IncytePharmaceuticals,Inc.,PaloAlto,California(GEMMicroarrays,GeneJetTMarray,LifeSeq®Databasewithestimated100,000genes,andLifeArrayMicroarraySoftware)IntelligentBio-Instruments,Cambridge,MassachusettsJMAR"sPrecisionSystems,Inc.,Chatsworth,CA.DesignerandmanufacturerofUVexposureandmaskalignersystemsspecificallydesignedforbio-chipmanufacturers.Alsoproducescustommicropositioningsystemsformicro-spottingequipmentandhighresolutiondimensionalmetrologyanddefectinspectionsystemsforqualityassuranceofbio-chipsandDNAmicro-arrays.LaBMAnAutomationLtd.,NorthYorkshire,TS95JY,UK(HDMS:LabmanHigh-DensityMicroarraySpotter)LifecodesCorp.,Stamford,Connecticut(LifecodesMicroArraySystem:LMAS)Micronics,Inc.,Redmond,Washington.microfluidicsbasedsystemsforapplicationtoclinicallaboratorydiagnostics:Microcytometer?,H-Filter?,T-Sensor?,andO.R.C.A.µFluidics.MolecularApplicationsGroup,PaloAlto,CA.Stingray?isintegratedsoftwareanddatabaseproductsforgeneexpression,genefunction,andgenesequenceanalysisfrommicroarraydata.ItisintegratedwithanddependentupontheuseofAffymetrix"sGeneChip®systemanditsExpressionDataMiningTool(EDMT)software.MolecularDynamics,Inc.,Sunnyvale,California(Storm®andFluorImager®MolecularTool,Inc.,Baltimore,Maryland.GeneticBitAnalysis,GBA®,Genomatic?.AcquiredbyOrchidBiocomputeronSeptember14,1998.Nanogen,SanDiego,California(ElectronicAddressing,Concentration,andHybridization)NENLifeScienceProducts,Boston,MA(MICROMAX?HumancDNAMicroarraySystemIfordifferentialgeneexpressionanalysis)OncormedInc.,(acquiredbyGeneLogicinJuly,1998)characterizesgenestoestablishtheirclinicalrelevancyandprovidesmolecularprofilingofpatientsforpharmacogenomicandtherapeuticpurposesOrchidBiocomputer,Inc.,Princeton,NewJersey(aSarnoffcompany)microfluidicchips;applyingmicrofabricationprocessesinglass,silicon,andothermaterialstocreatethreedimensionalstructures.Containedwithinthesedevicesaresmallcapillarychannelslessthanamillimeterwide.WinsNISTATPAwardin"ToolsforDNADiagnostics"Project:PolymeraseSignalingAssayforDNAVariationDetectiononUniversalProcessorArraysItalsohasaWebsiteonsinglenucleotidepolymorphisms(SNPs).PackardInstrumentCompany,Meriden,Connecticut.(BioChipArrayer)Partek,Inc.,St.Peters,Missouri.Providerofpatternrecognitionanddatavisualizationsoftwareforscienceandengineering.ItsPartekPro2000systemhasbeenusedbycompaniestoanalyzemicroarraygeneexpressiondata.PEAppliedBiosystems,WinsNISTATPAwardin"ToolsforDNADiagnostics"forproject:Integrated,Micro-SamplePreparationSystemforGeneticAnalysisPharmaSeq,Inc.,MonmouthJunction(nearPrinceton),NJ.Developerofmicrotransponder-basedtechnologyforDNAdiagnosticassays.WinsNISTATPAwardin"ToolsforDNADiagnostics"forproject:MultiplexDNADiagnosticAssayBasedonMicrotranspondersPhase-1MolecularToxicology,Inc.,SantaFe,NewMexico.Molecularandhighthroughputtoxicologyusinggenechips(LicensedfromXenometrix)Proteome,Inc.ProtogeneLaboratories,PaloAlto,California(Surfacetensionarrayonglasssubstrate;"Printing"reagentsusingdrop-on-demandtechnology)RadiusBiosciences,Medfield,MassachusettsResearchGenetics,Huntsville,Alabama(GeneFilter)RosettaInpharmatics,Kirkland,Washington.Scanalytics,Inc.,Fairfax,VA.ItsMicroArraySuiteenablesresearcherstoacquire,visualize,process,andanalyzegeneexpressionmicroarraydata.DevelopedbyscientistsattheNIH"sNationalHumanGenomeResearchInstitute.SequanaTherapeutics(mergedwithArrisPharmaceuticaltobecomeAxySPharmaceuticals),LaJolla,CaliforniaSequenom,Hamburg,Germany,andSanDiego,California(DNAMassArray,BiomassPROBE,BiomassSIZE,BiomassSEQUENCE,BiomassSCAN,BiomassINDEX,andSpectroChip)SiliconGenetics,RedwoodCity,California(GeneSpringworkbenchforanalyzingexperimentsbasedupongenomicexpressionexperiments)Spotfire,Inc.,Cambridge,Massachusetts.Offersadvanceddatavisualizationcapabilitiesincludingtheabilitytoperformgeneclusteranalysisandmetabolicpathwaymapping.TheSpotfireArrayExplorerisidealforanyresearcherperformingmicroarrayanalysis.SynomicsLtd.,Cambridge,UK(bioinformatics)Synteni,Inc.,Fremont,California(acquiredbyIncytePharmaceuticals,Inc.inJanuary1998)(UniGEM?GeneExpressionMicroarray)TeleChemInternational,Sunnyvale,California(offerswholesystemparts:ChipMaker,SmartChips,ArrayIt,HybridizationCassette,ScanArray3000,ImaGeneQuantificationSoftware)VirtekVisionInternationalInc.(Ontario,Canada)ChipReader?isahigh-sensitivitylaserconfocalsystemforrapidimagingoftheDNAmicroarrays.Vysis,Inc.,DownersGrove,Illinois(CGH-ComparativeGenomicHybridization)Xanthon,ResearchTrianglePark,NorthCarolina.developsmicroplatebasedmini-arraysforhighthroughputscreeningofcompoundsfortheireffectsongeneexpression.Xenometrix,Inc.,Boulder,CO(GeneProfileAssayandbioinformaticsforgeneinductionprofileanalysis;ademoisavailable)

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