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Adipogen/Adiponectin (rat) ELISA Kit/AG-45A-0005YEK-KI01/96 wells
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Specifications&Handling:ProductDataSynonymsACRP30;ADIpoQ;apM1;GBP28;Adipocytecomplementrelatedproteinof30kDaPropertiesApplicationSetQuantitativeELISASpecificityDetectsratadiponectin.Doesnotcross-reactwithmouseadiponectin,humanadiponectin,ratresistin,ratRELM-αorratleptin.CrossreactivityRatQuantity1x96wells2x96wells(TwinPlex)Sensitivity50pg/mlRange0.375to24ng/mlSampleTypeCellCultureSupernatant,Plasma,SerumAssayTypeSandwichDetectionTypeColorimetricProductTypeKitShippingandHandlingShippingBLUEICEShortTermStorage+4°CLongTermStorage+4°CHandlingAdviceAfterstandardreconstitution,preparealiquotsandstoreat-20°C.Avoidfreeze/thawcycles.Plateandreagentsshouldreachroomtemperaturebeforeuse.Use/StABIlity12monthsafterthedayofmanufacturing.SeeexpirydateonELISAKitbox.DocumentsManualDownloadMSDSDownloadRelatedProductsAdiponectin(human)ELISAKitAdiponectin(mouse)ELISAKitAdiponectin(rat)(rec.)anti-Adiponectin(rat),mAb(RADI264)anti-Adiponectin(rat),pAbanti-Adiponectin(rat),mAb(RADI06)Description:Adiponectin[ACRP30;AdipoQ]isapromisingbioMarkerofinsulinresistanceandtype2diabetesmellitus(T2DM)butalsoasapotentialtargetformanagementofthemetabolicsyndrome.Itisaveryrobustmarkerthatisnotpronetodegradationoracuteinflammatorychallenges,ispresentinrelativelyhighconcentrationsintheperipheralcirculation,andcanbecollectedbyavarietyofmethods.Thebenefitsofusingadiponectinassaysinclinicalsettingsinclude,(a)predictionofriskofdiabetesandmetabolicstatusand(b)providingatooltomonitormetabolicimprovements.Adiponectinexertsanti-atherogenicandanti-inflammatorypropertiesandmaybeimportantasabiomarkerforobesity-relatedcardiovasculardisease(CVD).NewfindingsshowedurinaryadiponectinexcretionasanindependentnewbiomarkerofmicrovascularandmacrovasculardamageinT2DMandsuggesteditasaverypromisingtoolforearlycardiovasculardiseaseriskassessment.Adiponectinserumlevelwasalsodescribedasagoodbiomarkerofcolorectaladenoma,thisbeingrelatedtothepositivecorrelationbetweenobesityandincreasedriskofcanceratvarioussites(colorectal,breast,prostateandendometrium).
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