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Adipogen/ANGPTL6 (human) ELISA Kit/AG-45A-0016YEK-KI01/96 wells
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Specifications&Handling:ProductDataSynonymsAngiopoietin-likeProtein6;AGF;Angiopoietin-relatedGrowthFactorPropertiesApplicationSetQuantitativeELISASpecificityDetectshumanANGPTL6.Doesnotcross-reactwithhumanANGPTL3,humanANGPTL4orhumanANGPTL7.CrossreactivityHumanQuantity1x96wellsSensitivity1.2ng/mlRange1.56to100ng/mlSampleTypeCellCultureSupernatant,Plasma,SerumAssayTypeSandwichDetectionTypeColorimetricProductTypeKitShippingandHandlingShippingBLUEICEShortTermStorage+4°CLongTermStorage+4°CHandlingAdviceAfterstandardreconstitution,preparealiquotsandstoreat-20°C.Avoidfreeze/thawcycles.Plateandreagentsshouldreachroomtemperaturebeforeuse.DocumentsManualDownloadMSDSDownloadRelatedProductsANGPTL6(human)(rec.)anti-ANGPTL6(human),pAbanti-ANGPTL6(human),pAbanti-ANGPTL6(human),mAb(Kairos-60)Description:SevenproteinscontaininganN-terminalcoiled-coildomainandaC-terminalfibrinogen-likedomain,bothcharacteristicsofangiopoietins,havebeenidentifiedandthereforedesignatedangiopoietin-likeproteins1-7(ANGPTL1-7).ANGPTL3andANGPTL6(Angiopoietin-relatedgrowthfactor;AGF),amongothers,functiontoregulateangiogenesisandalsoappeartodirectlyregulatelipid,glucoseandenergymetabolism.TheserumlevelsofANGPTL6aresignificantlyincreasedinobesehumans,patientswithtype2diabetesmellitus(T2DM)andinmetabolicsyndrome.Therefore,ANGPTL6maybeanovelbioMarkerformetabolicdiseasesandmayprovideanoveltherapeuticapproachtocounteractobesity,T2DMandinsulinresistance.
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