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Adipogen/Caspase-1 (mouse) Matched Pair Detection Set/AG-46B-0003-KI01/1 Set
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Specifications&Handling:ProductDataSynonymsInterleukin-1βConvertase;IL-1BC;Interleukin-1β-convertingEnzyme;ICEPropertiesApplicationSetQuantitativeELISASpecificityDetectsmouseCaspase-1(p10andp20domain).DoesnotdetecthumanCaspase-1.CrossreactivityMouseQuantityContainssufficientmaterialstorunELISAson5x96-wellplates.Sensitivity50pg/mlRange0.15ng/mlto10ng/ml.SampleTypeCellCultureSupernatantAssayTypeSandwichDetectionTypeColorimetricKitContains1vialstandardprotein(1μg)(lyophilized)[STD]1vialcoatingantibody(120μg)[COAT]1vialdetectionantibody(60μg)[DET]1vialstreptavidin-HRP(10μg)(lyophilized)[STREP]ProductTypeKitShippingandHandlingShippingBLUEICEShortTermStorage-20°CLongTermStorage-20°CHandlingAdviceAvoidfreeze/thawcycles.Use/StABIlityStableforatleast1yearafterreceiptwhenstoredat-20°C.DocumentsManualDownloadMSDSDownloadRelatedProductsCaspase-1(mouse)ELISAKitanti-Caspase-11(p20)(mouse),mAb(Flamy-2)anti-Caspase-1(p10)(mouse),mAb(Casper-2)(Biotin)anti-Caspase-1(p20)(mouse),mAb(Casper-1)(Biotin)anti-Caspase-1(p10)(mouse),mAb(Casper-2)anti-Caspase-1(p20)(mouse),mAb(Casper-1)Description:Caspase-1isthebest-describedinflammatorycaspase.Itprocessesthecytokinesinterleukin-1β(IL-1β)andinterleukin-18(IL-18)andinducespyroptoticcelldeath.Caspase-1isactivatedbymultiproteincomplexescalledinflammasomesinresponsetonumerousstimulithataredetectedthroughdistinctinflammasomes.NLRC4respondstocytosolicflagellin,murineNLRP1brespondstoanthraxlethaltoxin,AIM2respondstocytosolicDNAandNLRP3/NALP3respondstoavarietyofagoNISTsincludingcrystals.Thecaspase-1(mouse)MatchedPairDetectionSetcontainsallreagentsforthedevelopmentofasandwichELISAtomeasurecaspase-1(mouse)incellculturesupernatants.ThisMatchedPairDetectionSetisaquantitativedetectionmethod,alternativetoWesternblottingtomeasurecaspase-1secretion.
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