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Adipogen/IL-33 (human) ELISA Kit/AG-45A-0033YEK-KI01/96 wells
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Specifications&Handling:ProductDataSynonymsNF-HEV;Interleukin-33;IL-1F11PropertiesApplicationSetQuantitativeELISASpecificityDetectshumanIL-33.Doesnotcross-reactwithmouseIL-33,humanIL-6,humanIL-24,humanIL-23,humanIL-17AorhumanST2.CrossreactivityHumanQuantity1x96wellsSensitivity5pg/mlRange0.016to1ng/mlSampleTypeCellCultureSupernatant,Plasma,SerumAssayTypeSandwichDetectionTypeColorimetricProductTypeKitShippingandHandlingShippingBLUEICEShortTermStorage+4°CLongTermStorage+4°CHandlingAdviceAfterstandardreconstitution,preparealiquotsandstoreat-20°C.Avoidfreeze/thawcycles.Plateandreagentsshouldreachroomtemperaturebeforeuse.Use/StABIlity12monthsafterthedayofmanufacturing.SeeexpirydateonELISAKitbox.DocumentsManualDownloadMSDSDownloadRelatedProductsanti-IL-33(mouse),mAb(rec.)(blocking)(Bondy-1-1)(preservativefree)anti-IL-33(mouse),mAb(rec.)(blocking)(Bondy-1-1)IL-33(human)(rec.)(untagged)(BULK)IL-33(human)(rec.)(untagged)Description:Interleukin-33(IL-33;HF-NEV;IL-1F11),amemberoftheIL-1familyofcytokines,isexpressedbymanycelltypesfollowingpro-inflammatorystimulationandisthoughttobereleasedoncelllysis.IL-33affectsthevariouscelltypesthatexpressmembraneST2,whichisselectivelyexpressedbyTh2butnotTh1cells.TheabilityofIL-33totargetnumerousimmunecelltypes,likeTh2-likecells,mastcells,andB1cells,andtoinducecytokineandchemokineproductionunderlinesitspotentialininfluencingtheoutcomeofawiderangeofdiseases,suchasarthritis,asthma,atopicallergy&anaphylaxis,cardiovasculardisease/atherosclerosis,nervoussystemdiseases,andsepsis.InhealthyhumanserumalmostnoIL-33couldbedetected,whereasserumIL-33levelsweresignificantlyincreasedinchronicactiveinflammation,likerheumatoidarthritis.
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