首页 > Adipogen > Adipogen/anti-α-1 Microglobulin, mAb (10A12)/YIF-LF-MA0226/100 µl

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Adipogen/anti-α-1 Microglobulin, mAb (10A12)/YIF-LF-MA0226/100 µl

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YIF-LF-MA0226

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Adipogen

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MoreInformationProductDetailsSynonymsHCP;AMBP;ProteinHC;α-1Microglycoprotein;Complex-formingGlycoproteinHeterogeneousinChargeProductTypeMonoclonalAntibodyPropertiesClone10A12IsotypeMouseIgG1κImmunogen/AntigenProteinpurifiedfromhumanplasma.ApplicationELISAWesternBlot(1:2,000)CrossreactivityHumanPurityDetailAmmoniumsulfateprecipitation.FormulationLiquid.HEPESwith0.15MNaCl,0.01%BSA,0.03%sodiumazide,and50%glycerol.OtherProductDataClickhereforOriginalManufacturerProductDatasheetOurproductdescriptionmaydifferslightlyfromtheoriginalmanufacturersproductdatasheet.DeclarationManufacturedbyAbFrontierShippingandHandlingShippingBLUEICEShortTermStorage+4°CLongTermStorage-20°CUse/StABIlityStableforatleast1yearafterreceiptwhenstoredat-20°C.DocumentsMSDSNoProductSpecificationSheetDatasheetDownloadPDFα1-microglobulin(proteinHC)isalipocalinwithimmunosuppressiveproperties.Thelipocalinsareafamilyofproteinswhichtransportsmallhydrophobicmoleculessuchassteroids,bilins,retinoids,andlipids.Wellknownlipocalinsareα1-microglobulin,α-1-acidglycoprotein(orosomucoid),apolipoproteinD,β-lactoglobulin,andcomplementcomponentC8γchainetc.Ageneinthelipocalinclusterencodesα1-microglobulintogetherwithaKunitz-typeproteinaseinhibitor,bikunin.Thegeneistranslatedintotheα1-microglobulin-bikuninprecursor,whichissubsequentlycleavedandthetwoproteinssecretedtothebloodseparately.α1-microglobulin,isamonomericproteinofamolecularsizeof27kDa.Itisproducedbytheliverandcirculatesinafreeform,butisalsoboundincomplexestohighmolecularweightmolecules.Inhumanplasma,approx.50%ofα1-microglobulinformsaone-to-onecomplexwithmonomericimmunoglobulinA(IgA)byareductionresistantbond.Normalurinecontainsverysmallamountsofα1-microglobulin.Inconditionswithdisturbedtubularfunction,reabsorptionofα1-microglobulinisreducedandincreasedamountsarefoundinurine.Urinaryα1-microglobulinseemsapromisingMarkerforrenalabnormalitiesandforthedifferentiationofvariousnephrologicalandurologicalpathologies.Inter-α-trypsininhibitorinhibitstrypsin,plasmin,andlysosomalgranulocyticelastase.Inhibitscalciumoxalatecrystallization.ProductReferences1)PendersJandDelangheJR,(2004)ClinChimActa.346(2):107-118.(General)2)BoAkerstrometal.,(2000)BiochimBiophysActa.1482(1-2):172-184.(General)3)XuSandVengeP,(2000)BiochimBiophysActa.1482(1-2):298-307.(General)

Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。