首页 > Adipogen > Adipogen/anti-α-Tubulin, mAb (rec.) (F2C) (ATTO 488)/AG-27B-0005TD-C100/100 µg

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Adipogen/anti-α-Tubulin, mAb (rec.) (F2C) (ATTO 488)/AG-27B-0005TD-C100/100 µg

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AG-27B-0005TD-C100

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Adipogen

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MoreInformationProductDetailsProductTypeRecombinantAntibodyPropertiesCloneF2CIsotypeHumanIgG2&lamBDa;Source/HostPurifiedfrom HEK293cell culturesupernatant.Immunogen/AntigenBovinebraintubulin.Label/ConjugatesATTO488ApplicationImmunocytochemistry:(1:1"000)CrossreactivityBovineHumanMouseSpecificityRecognizesmouse,bovineandhumanα-tubulin.Purity≥95%(SDS-PAGE)PurityDetailProteinA-affinitypurified.Concentration1mg/mlFormulationLiquid.InPBScontaining0.02%sodiumazide.OtherProductDataanti-α-Tubulin,monoclonalantibody(recombinant)(F2C)(ATTO488)iscomposedofhumanvariableregions(VHandVL)(λ-chain)ofimmunoglobulinfusedtothehumanlgG2Fcdomain.anti-α-Tubulin,monoclonalantibody(recombinant)(F2C)(ATTO488)isanantibodydevelopedbyantibodyphagedisplaytechnologyusingahumannaiveantibodygenelibrary.TheselibrariesconsistofscFv(singlechainfragmentvariable)composedofVH(variabledomainofthehumanimmunoglobulinheavychain)andVL(variabledomainofthehumanimmunoglobulinlightchain)connectedbyapolypeptidelinker.Theantibodyfragmentsaredisplayedonthesurfaceoffilamentousbacteriophage(M13).ThisscFvwasselectedbyaffinityselectiononantigeninaprocesstermedpanning.Multipleroundsofpanningareperformedtoenrichforantigen-specificscFv-phage.Monoclonalantibodiesaresubsequentlyidentifiedbyscreeningaftereachroundofselection.TheselectedmonoclonalscFvisclonedintoanappropriatevectorcontainingaFcportionofinterestandthenproducedinmammaliancellstogenerateanIgGlikescFv-Fcfusionprotein.ShippingandHandlingShippingBLUEICEShortTermStorage+4°CLongTermStorage+4°CUse/StABIlityKeepconjugatedformatsat+4°C.Stableforatleast1yearafterreceiptwhenstoredat+4°C.DocumentsProtocolsDownloadPDFMSDSDownloadPDFProductSpecificationSheetDatasheetDownloadPDFTubulinisthemajorbuildingblockofmicrotubules.Thisintracellularcylindricalfilamentousstructureispresentinalmostalleukaryoticcells.Microtubulesfunctionasstructuralandmobileelementsinmitosis,intracellulartransport,flagellarmovement,andtheCytoskeleton.ProductReferencesRecombinantantibodiesselectedagainstsubcellularfractionstotrackendogenousproteindynamicsinvivo:C.Nizak,etal.;Traffic7,739(2003)Characterizationofsinglechainantibodytargetsthroughyeasttwohybrid:O.Vielemeyer,etal;BMCBiotechnol.10,59(2010)

Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。