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PBL/Anti-Human IFN Alpha Antibody, Clone MMHA-1, neutralizing (MAb)/50 μg/21105-1
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Anti-Human IFN Alpha Antibody, Clone MMHA-1, neutralizing (MAb)Home / Products / Antibodies / Monoclonal Antibodies (MAbs) / Anti-Human IFN MAbs / Anti-Human IFN Alpha Antibody, Clone MMHA-1, neutralizing (MAb)Product Features:Mouse monoclonal antibody against Human IFN Alpha (Clone MMHA-1)Suitable for use in neutralization and ELISAsUnconjugated OrderingCatalog No. Pack Size Price Quantity 21105-1 50 μg$335.00 SpecificationsTech Info / DataCitationsDocumentationSpecificationsFormulationSupplied frozen in phosphate-buffered saline (PBS) containing 0.1% Bovine Serum Albumin (BSA)AntigenRecombinant human interferon alpha 2IsotypeIgG1 kappaHost SpeciesMousePurity> 95% by SDS-PAGE stained by Coomassie BlueEndotoxin level < 1 EU/μgBioactivityMeasured by neutralization of interferon in cytopathic effect inhibition assay.SpecificityNeutralizes human IFN-alpha; binds to human IFN-alphaStorageFor retention of full activity store at -70°C or below and avoid repeated freeze/thaw cyclesAntigen SynonymsNoneCloneMMHA-1 Tech Info / DataTested Applications:NeutralizationELISA Citations4 Citations:Saidi, Hela, et al. (2016). HMGB1 Is Involved in IFN-α Production and TRAIL Expression by HIV-1-Exposed Plasmacytoid Dendritic Cells: Impact of the Crosstalk with NK Cells. PLOS Pathogens, 30 pgs. PMID: 26871575. (link)Kalb, Madeleine, et al. (2012). TRAIL(+) human plasmacytoid dendritic cells kill tumor cells in vitro: mechanisms of imiquimod- and IFN-α-mediated antitumor reactivity. Journal of Immunology, 10 pgs. PMID: 22231699. (link)Stary, Georg, et al. (2009). Plasmacytoid dendritic cells express TRAIL and induce CD4+ T-cell apoptosis in HIV-1 viremic patients. Blood Journal, 11 pgs. PMID: 19690337. (link)Piccioli, Diego, et al. (2002). Contact-dependent Stimulation and Inhibition of Dendritic Cells by Natural Killer Cells. JEM, 7 pgs. PMID: 11828008. (link) Documentation 21105-1 Certificate of Analysis (CoA) SDS

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