Anti-Human IFN Alpha Antibody, Clone MMHA-11, neutralizing (MAb)Home / Products / Antibodies / Monoclonal Antibodies (MAbs) / Anti-Human IFN MAbs / Anti-Human IFN Alpha Antibody, Clone MMHA-11, neutralizing (MAb)Product Features:Mouse monoclonal antibody against Human IFN Alpha (Clone MMHA-11)Suitable for use in neutralization and ELISAsUnconjugated OrderingCatalog No. Pack Size Price Quantity 21112-1 50 μg$295.00 SpecificationsTech Info / DataCitationsDocumentationSpecificationsFormulationSupplied frozen in phosphate-buffered saline (PBS) containing 0.1% Bovine Serum Albumin (BSA)AntigenHuman leukocyte interferonIsotypeIgG1 kappaHost SpeciesMousePurity> 95% by SDS-PAGE stained by Coomassie BlueEndotoxin level < 1 EU/μgBioactivityMeasured by neutralization of interferon in cytopathic effect inhibition assay.SpecificityNeutralizes human IFN-alpha; binds to human IFN-alphaStorageFor retention of full activity store at -70°C or below and avoid repeated freeze/thaw cyclesAntigen SynonymsIFN alpha MAb, IFN-a, interferon alpha monoclonal, IFN alpha 2, IFN-a2, interferon alpha 2, Leukocyte interferon, Leukocyte IFN, alpha interferon, interferon alfa, IFN alfa, interferon alpha 2a, IFN alpha 2a, interferon a, interferon alpha 2b, IFN alpha 2b, Type I interferon alpha, Type I IFN alphaCloneMMHA-11 Tech Info / DataTips, Tools and Troubleshooting:Antibodies against Human IFN-α Subtype Specificities Comparison Chart (link)Tested Applications:NeutralizationELISA Citations6 Citations:Gujer, et al. (2011). Human and Rhesus Plasmacytoid Dendritic Cell and B-Cell Responses to Toll-Like Receptor Stimulation. Immunology, 13 pgs. PMID: 21977996. (link)Richez, C, et al. (2009). TLR4 ligands induce IFN-alpha production by mouse conventional dendritic cells and human monocytes after IFN-beta priming. Journal of Immunology. PMID: 19124725. (link)Gantier, Michael, et al. (2008). TLR7 is involved in sequence-specific sensing of single-stranded RNAs in human macrophages. Journal of Immunology, 9 pgs. PMID: 18250417. (link)Lee, Pui, et al. (2007). Type I interferon as a novel risk factor for endothelial progenitor cell depletion and endothelial dysfunction in systemic lupus erythematosus. Arthritis & Rheumatism, 11 pgs. PMID: 17968925. (link)Foley, et al. (2005). Roles for CXC Chemokine Ligands 10 and 11 in Recruiting CD4+ T Cells to HIV-1-Infected Monocyte-Derived Macrophage, Dendritic Cells, and Lymph Nodes. Journal of Immunology, 10 pgs. PMID: 15814716. (link)Fagnoni, et al. (2004). Reconstitution Dynamics of Plasmacytoid and Myeloid Dendritic Cell Precursors After Allogenic Myeloablative Hematopoietic Stem Cell Transplantation. Blood Journal, 10 pgs. PMID: 15010368. (link) Documentation 21112-1 Certificate of Analysis (CoA) SDS Mouse MAb to Human IFN Alpha Titration in A549