Anti-Human IFNAR2 Antibody, Clone MMHAR-2, neutralizing (MAb)Home / Products / Antibodies / Monoclonal Antibodies (MAbs) / Anti-Human IFN MAbs / Anti-Human IFNAR2 Antibody, Clone MMHAR-2, neutralizing (MAb)Product Features:Anti-IFNAR2 antibody (clone MMHAR-2) to human Interferon (Alpha, Beta and Omega) Receptor 2Blocks the biological action of Human Type I InterferonsSuitable for use in Type I IFN neutralization, flow cytometry, immunohistochemistry, and immunoprecipitationFull Product Name: Anti-Human Interferon Alpha/Beta Receptor Chain 2, Clone MMHAR-2 (MAb) OrderingCatalog No. Pack Size Price Quantity 21385-1 50 μg$495.00$575.00 SpecificationsTech Info / DataCitationsDocumentationSpecificationsFormulationSupplied frozen in phosphate-buffered saline (PBS) containing 0.1% Bovine Serum Albumin (BSA)AntigenHuman interferon alpha/beta receptor chain 2 (Human IFNAR2)IsotypeIgG2AHost SpeciesMousePurity> 95% by SDS-PAGE stained by Coomassie BlueEndotoxin level < 1 EU/μgBioactivityMeasured by neutralization of interferon in cytopathic effect inhibition assay.SpecificityNeutralizes human IFN-alpha receptor; interacts with extracellular domain; binds to human IFN-alpha receptor with high affinity; blocks biological action of Type I IFNsStorageFor retention of full activity store at -70°C or below and avoid repeated freeze/thaw cyclesAntigen SynonymsNoneCloneMMHAR-2 Tech Info / DataTested Applications:NeutralizationSuggested Applications*:Immunoprecipitation (1-5 μg/ml)Immunohistochemistry (1 μg/ml)Flow Cytometry (1-10 μg/ml)*Please note that these applications are presented for suggested use only and have not been fully evaluated by PBL.  Background:The Type I interferon receptor is a heterodimer consisting of IFNAR1 and IFNAR2. 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Identification of a Novel Subunit of the Type I Interferon Receptor Localized to Human Chromosome 21. JBC, 5 pgs. PMID: 8496154. (link)Reference:Colamonici, Oscar, et al. (1993). Identification of a Novel Subunit of the Type I Interferon Receptor Localized to Human Chromosome 21. JBC, 5 pgs. PMID: 8496154. (link) Documentation 21385-1 Certificate of Analysis (CoA) SDS Neutralization Effect of PBL Anti-Human IFNAR2 Monoclonal Antibody (21385) on Human IFN Alpha 2a (11100) and IFN Beta (11415) Activities in an A549 Cell/EMCV CPE Assay