Human IFN Alpha D (Alpha 1)Home / Products / Proteins / Interferons / Human IFN Proteins / Human IFN Alpha D (Alpha 1)Product Features:Human IFN Alpha 1 recombinant protein expressed in E.coliExpression is induced by viral infectionEncoding gene IFNA1 at position Val114 OrderingCatalog No. Pack Size Price Quantity 11125-1 1 x 105 units$280.00 SpecificationsTech Info / DataCitationsDocumentationSpecificationsFormulationSupplied frozen in phosphate-buffered saline (PBS) containing 0.1% Bovine Serum Albumin (BSA)Molecular Weight19.4 kDaSourcecDNA obtained from human leukocyte mRNA expressed in E.coliPurity> 95% by SDS-PAGE stained by Coomassie Blue BioactivityMeasured using a cytopathic inhibition assay on Bovine Kidney Cells (MDBK) with Vesicular Stomatis Virus (VSV); human lung carcinoma cell line A549 with encephalomyocarditis virus (EMCV)StorageFor retention of full activity store at -70 ºC or below and avoid repeated freeze-thaw cyclesSynonymsHu-[Val114] IFN-α1 Accession NumberV00538 Tech Info / DataBackground:Recombinant Human Interferon Alpha D (Hu-IFN-alpha D; Hu-[Val114] IFN-alpha 1) obtained from human leukocyte mRNA expressed in E.coli.IFN alpha 1 is one of the many interferon alpha subtypes belonging to the Type I leukocyte IFN family. The Type I IFN family has antiviral, anti-proliferative and natural killer cell activities. Citations3 Citations:Wilson, Timothy R, et al. (2012). Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors. Nature, 12 pgs. PMID: 22763448. (link)Wu, TG, et al. (2007). IFN-alpha-induced murine B16 melanoma cancer vaccine cells: induction and accumulation of cell-associated IL-15. Journal of Interferon & Cytokine Research. PMID: 17266439. (link)Kang, Dong-Chul, et al. (2004). Expression Analysis and Genomic Characterization of Human Melanoma Differentiation Associated Gene-5, mda-5: a Novel Type I Interferon-Responsive Apoptosis-Inducing Gene. Oncogene, 12 pgs. PMID: 14676839. (link) Documentation 11125-1 Certificate of Analysis (CoA) SDS Human IFN Alpha D (Alpha 1) Titration in A549