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MD Biosciences/Cartilage Link Protein, Antibody/100 ug/1042013
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OverviewData/SpecificationsLiterature/SupportHow To UseRelated ProductsOverviewOverview:Cartilage-link protein (LP) is a glycoprotein present in cartilage that stabilizes the interaction of aggrecan (versican) with hyaluronic acid (HA) in large proteoglycan aggregates.Related Terms/Symbols:Anti-HAPLN1 antibodyCRTL1Hyaluronan and proteoglycan link protein 1LPProteoglycan link proteinCartilage-linking protein 1HAPLN1 geneP10915Data/SpecificationsData/Specifications:Immunogen: Link Protein from Bovine nasal cartilageClone: 8A4Host: MouseIsotype: IgGSpecificity: This antibody recognizes the structurally related amino acid sequence epitopes … PISRP…and ….PITKP that occur in the two proteoglycan tandem repeat motifs of cartilage LP. Thisantibody can be used to detect intact LP 1,2 & 3 as well as a large number of smaller fragmentsthat are generated through proteolytic cleavage during LP catabolism. It recognizesLP in all animal species from chicken to humans.Purity: Affinity purifiedForm: Clear liquidConcentration: 0.1 mg/mLStorage: -20° CLiterature/SupportLiterature/Support/Publications:Antibody to Cartilage Link Protein Insert (PDF, 328 KB)Joint Disease and Aggrecan (blog post)How To UseHow To Use:ApplicationsWestern BlotIHCRIATechnical NotesNo enzyme pretreatment required, however chondroitinase and hyaluronidase will increaseantibody sensitivity by exposing epitopes. For WB chondroitinase and hyaluronidase treatmentis recommended.Related ProductsRelated Products:Aggrecan Antibody, C-terminal neoepitope NITEGEAggrecan Antibody, N-terminal neoepitope ARGAggrecan Antibody, N-terminal neoepitope DIPENAggrecan Antibody, N-terminal neoepitope FFGVAggrecan IGD Antibody
MD Biosciences 是针对药物和诊断资产开发的临床前，转化和临床阶段合同研究服务的供应商。通过AAALAC 认证，符合 GLP 的 CLIA 设施，在广泛的治疗领域提供服务和产品，包括炎性疾病，自身免疫，神经病学，肿瘤学，新陈代谢和疼痛。为了在每个专业领域提供最优质的产品和专业知识并优化研究，设有 4 个独立的部门：MD Biosciences炎症/免疫学服务、MD Biosciences神经病学发现服务、MD Biosciences组织病理学服务和MD Bioproducts。
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