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DescriptionCatalogueNumberAB15452BrandFamilyChemicon®TradeNameChemiconDescriptionAnti-MAP2AntibodyAlternateNamesMicrotubuleassociatedprotein2ProductInformationFormatAffinityPurifiedPresentationAffinitypurifiedchickenimmunoglobulin.Twodifferentantibodieswerecombinedtomakethisproduct.LiquidinPBS,pH7.2with0.02%sodiumazide.StorageandShippingInformationStorageConditionsMaintainat2-8°Cinundilutedaliquotsforupto6monthsafterdateofreceipt.ApplicationsApplicationAnti-MAP2AntibodydetectslevelofMAP2&hasbeenpublished&validatedforuseinIC,IH.KeyApplicationsImmunocytochemistryImmunohistochemistryApplicationNotesImmunohistochemistry:1:1000-1:2,000using2%paraformaldehydefixedtissue.Immunocytochemistry:1:1000-1:2,000using2%paraformaldehydefixedcells.Optimalworkingdilutionsmustbedeterminedbyenduser.BIOLOGicalInformationImmunogenSyntheticpeptidescorrespondingtodifferentregionsofthehuman/mouseMAP2protein.HostChickenSpecificityMAP2[Microtubuleassociatedprotein2]SpeciesReactivityMouseSpeciesReactivityNoteOtherspecieshavenotyetbeentested.Itisexpectedthattheantibodywillalsoreactwithhumanduetoimmunogensequencesimilarity.AntibodyTypePolyclonalAntibodyEntrezGeneNumberNM_001039538.1NM_002374.3NM_031845.2NM_031847.2EntrezGeneSummaryThisgeneencodesaproteinthatbelongstothemicrotubule-associatedproteinfamily.Theproteinsofthisfamilyarethoughttobeinvolvedinmicrotubuleassembly,whichisanessentialstepinneurogenesis.Theproductsofsimilargenesinratandmouseareneuron-specificcytoskeletalproteinsthatareenrichedindentrites,implicatingaroleindeterminingandstABIlizingdentriticshapeduringneurondevelopment.Anumberofalternativelysplicedvariantsencodingdistinctisformshavebeendescribed.GeneSymbolMAP2MAP2BMAP-2MAP2CDKFZp686I2148MAP2APurificationMethodImmunoAffinityPurifiedUniProtNumberP11137UniProtSummaryFUNCTION:SwissProt:P11137#TheexactfunctionofMAP2isunknownbutMAPsmaystabilizethemicrotubulesagainstdepolymerization.Theyalsoseemtohaveastiffeningeffectonmicrotubules.SIZE:1827aminoacids;199539DaPTM:MAP2A/cisphosphorylated.PhosphorylateduponDNAdamage,probablybyATMorATR.SIMILARITY:SwissProt:P11137##Contains3Tau/MAPrepeats.PhysicochemicalInformationDimensionsMaterialsInformationMaterialsInformation
密理博(Millipore)公司成立于1954年,总部位于美国麻省,在全世界设有47个办事处,为100多个国家提供产品和技术服务。目前全球雇员超过5800人,在美国、法国和日本等国家拥有7家大型生产工厂,主要生产过滤膜及膜过滤产品。
20世纪80年代,密理博公司进入中国市场。先后在香港、北京、上海、广州及成都设立了办事机构,并于2000年4月在上海浦东外高桥保税区建立了密理博(上海)贸易有限公司。
为了更好地满足中国用户的需求,密理博中国主页于2006年11月向广大用户开放,介绍密理博中国有限公司的最新动态,力求为用户打造专业的产品与服务信息交流平台。
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