首页 > Millipore > Millipore/AB1620 | Anti-Vimentin Antibody/AB1620/500 µL

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Millipore/AB1620 | Anti-Vimentin Antibody/AB1620/500 µL

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DescriptionCatalogueNumberAB1620BrandFamilyChemicon®TradeNameChemiconDescriptionAnti-VimentinAntibodyProductInformationFormatSerumControlBreastcarcinomatissue,Colon,Prostate,Tonsil,Tonsilarlymphoma,Uterus,UreterPresentationNeatgoatSerum.Liquidcontaining0.1%sodiumazide.StorageandShippingInformationStorageConditionsMaintainfor1yearat-20°Cfromdateofshipment.Aliquottoavoidrepeatedfreezingandthawing.Formaximumrecoveryofproduct,centrifugetheoriginalvialafterthawingandpriortoremovingthecap.ApplicationsApplicationAnti-VimentinAntibodydetectslevelofVimentin&hasbeenpublished&validatedforuseinIC,IH,IH(P)&WB.KeyApplicationsImmunocytochemistryImmunohistochemistryImmunohistochemistry(Paraffin)WesternBlottingApplicationNotesImmunohistochemistry:1:20-1:40.Showsreactivityonfrozentissuesectionsaswellasformalin-fixedparaffinembeddedtissuebyimmunoperoxidaseandimmunofluorescentassays.ImmunocytochemistryWesternblotOptimalworkingdilutionsmustbedeterminedbyenduser.BIOLOGicalInformationImmunogenVimentinpurifiedfromculturedhumanforeskinfibroblasts.ConcentrationPleaserefertotheCertificateofAnalysisforthelot-specificconcentration.HostGoatSpecificityRecognizesvimentininculturedmammaliancellsandtissuesections.AB1620specificallystainsthevimentinband(58kD)usingtotalcellortissueextractsinimmunoblotting.Noreactivitytodesmin,keratin,neurofilamentsorglialfilaments.Showswidecross-reactivityamongmammalianspeciesusingvariousimmunolabelingtechniques.SpeciesReactivityHumanMammalsAntibodyTypePolyclonalAntibodyEntrezGeneNumberNM_003380.2EntrezGeneSummaryAlongwiththeMICROFILaments(actins)andmicrotubules(tubulins),theintermediatefilamentsrepresentathirdclassofwell-characterizedcytoskeletalelements.Thesubunitsdisplayatissue-specificpatternofexpression.Desmin(MIM125660)isthesubunitspecificformuscleandvimentinthesubunitspecificformesenchymaltissue.[suppliedbyOMIM]GeneSymbolVIMFLJ36605Vimentin.vimentinPurificationMethodUnpurifiedUniProtNumberP08670UniProtSummaryFUNCTION:SwissProt:P08670#Vimentinsareclass-IIIintermediatefilamentsfoundinvariousnon-epithelialcells,especiallymesenchymalcells.SIZE:466aminoacids;53652DaSUBUNIT:Homopolymer.ComponentofacomplexcomposedatleastofACTB,AP2M1,AP2A1,AP2A2,MEGF10andVIM.InteractswithHCVcoreprotein.TISSUESPECIFICITY:Highlyexpressedinfibroblasts,someexpressioninT-andB-lymphocytes,andlittleornoexpressioninBurkitt"slymphomacelllines.Expressedinmanyhormone-independentmammarycarcinomacelllines.PTM:Oneofthemostprominentphosphoproteinsinvariouscellsofmesenchymalorigin.Phosphorylationisenhancedduringcelldivision,atwhichtimevimentinfilamentsaresignificantlyreorganized.SIMILARITY:SwissProt:P08670##Belongstotheintermediatefilamentfamily.MolecularWeight58kDaPhysicochemicalInformationDimensionsMaterialsInformationMaterialsInformation

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20世纪80年代，密理博公司进入中国市场。先后在香港、北京、上海、广州及成都设立了办事机构，并于2000年4月在上海浦东外高桥保税区建立了密理博（上海）贸易有限公司。

为了更好地满足中国用户的需求，密理博中国主页于2006年11月向广大用户开放，介绍密理博中国有限公司的最新动态，力求为用户打造专业的产品与服务信息交流平台。