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QED Bioscience/DC-UbP/11094/1 Ea
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productdatasheetAnti-DC-UbPAntibodyORDERINGINFORMATIONCatalogNo.:11094Size:100ugIgGinPBS,pH7.4,purifiedbyimmunoaffinitychroma-tography.BACKGROUNDDC-UbPisa26kDaubiquitin-likeproteinfromdendriticcellscomprisedof106aminoacids.TheubiquitindomaininDC-UbPshares28.6%identitywithubiquitin,butitdoesnothavetheconservedC-terminusGly-Glyofubiquitinrequiredforubiquitinization.DC-UbPisfoundincytoplasm(particularlyinmitochondria),andDC-UbPmRNAisexpressedinvarioustumorcelltypes,butnotinnormaladulthumantissues,whichsuggestsaroleforDC-UbPintumOrigenesis.Inaddition,DC-UbPappearstobedownregulatedduringcellulardifferentiationandapoptosis.BACKGROUNDREFERENCELiuS,etal.2003BiochemBiophysResCommun300:800-805.Forinvitroinvestigationaluseonly.Notforuseintherapeuticordiagnosticprocedures.SPECIFICATIONSUMMARYImmunogen:Syntheticpeptidecorrespondingtoaminoacids197-212(SGRPLTDKMKFEELKI)ofhumanDC-UbPprecursorconjugatedtoKLHattheN-terminus.Thissequenceis93%identicalwiththoseofmouseandratDC-UbP.HostSpecies:RabbitStABIlizers:NonePreservatives:None.Availableonrequest.SPECIFICITYThisantibodyrecognizeshuman,mouse,andratDC-UbP.APPLICATIONSELISA:1:1,000-1:10,000withDc-UbPonthesolidphase.Theinvestigatorshoulddeterminetheoptimaldilutionfortheirapplication.DILUTIONINSTRUCTIONSDiluteinPBSormediumwhichisidenticaltothatusedintheassaysystem.STORAGEANDSTABILITYThisantibodyisstableforatleastone(1)yearat-20oC.Avoidmultiplefreeze-thawcycles.QEDBioscience,Inc.10919TechnologyPlace,SuiteCSanDiego,CA92127TollFree800.929.2114Phone858.675.2405Fax858.592.1509info@qedbio.comVisitourwebsiteforadditionalproductinformationandtoorderonline.qedbio.com
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