OVERVIEW: Synonyms Monoclonal Troponin I antibody (Cardiac), Anti-Troponin I antibody (Cardiac) Specificity Human Cross Reactivity To be determined by end-user Applications ELISA, IHC, IP, WB Immunogen Troponin I antibody (cardiac) was raised in mouse using animo acid residues 169-178 of cTnI as the immunogen. SPECIFICATIONS: Host Mouse Clone M9011522 Isotype IgG2a Method of Purification Troponin I antibody (Cardiac) was purified by chromatography on protein A Sepharose. Form & Buffer Protein A purified IgG supplied in PBS, pH 7.4, 0.1 % NaN3. Concentration Batch dependent - please inquire should you have specific requirements STORAGE & SAFETY: Storage Store at 4 deg C. Biohazard Information This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product. Usage Assay Information: Usage Recommendations Optimal conditions to be determined by end user GENERAL INFORMATION: Biological Significance Human troponin I is presented in cardiac muscle tissue by a single isoform with molecular weight 23876 Da and it consists of 209 amino acid residues. cTnI molecule contains two serines in the 22 and 23 positions. Both amino acid residues can be phosphorylated in vivo by protein kinase A, so four forms of protein ? one dephospho, two monophospho and one bisphospho ? can coexist in the cell.