OVERVIEW: Synonyms Monoclonal CD20 antibody, Anti-CD20 antibody, CD-20, CD 20 antibody, CD20, CD 20, CD-20 antibody Specificity Human Cross Reactivity To be determined by end-user Applications IHC, WB Immunogen CD20 antibody was raised in mouse using prokaryotic recombinant fusion protein corresponding to the c-terminal intracellular domain of the transmembrane CD20 molecule as the immunogen. SPECIFICATIONS: Host Mouse Clone 7D1 Isotype IgG1 Form & Buffer Lyophilized tissue culture supernatant containing 15mM NaN3. Reconstitute with 1 ml of sterile distilled water. STORAGE & SAFETY: Storage Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze-thaw cycles. Biohazard Information This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling. Usage Assay Information: Usage Recommendations IHC: 1:100-1:200, WB: 1:50-1:100 GENERAL INFORMATION: Biological Significance B-lymphocyte antigen CD20 or CD20 is an activated-glycosylated phosphoprotein expressed on the surface of all mature B-cells. In humans CD20 is encoded by the MS4A1 gene. This gene encodes a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues.