OVERVIEW: Synonyms Monoclonal CD31 antibody, Anti-CD31 antibody, Platelet Endothelial Cell Adhesion Molecule antibody, EndoCAM antibody, GPIIA antibody, PECAM1 antibody, PECAM-1 antibody, CD 31 antibody, CD-31, CD-31 antibody, CD 31, CD31 Specificity Human Cross Reactivity To be determined by end-user Applications IHC-P Immunogen CD31 antibody was raised in mouse using prokaryortic recombinant fusion of protein corresponding to a portion of the extracelluar domain downstream of the signal sequence of the CD31 molecule as the immunogen. SPECIFICATIONS: Host Mouse Clone 1A10 Isotype IgG1 Form & Buffer Lyophilized tissue culture supernatant containing 15mM NaN3. Reconstitute with 1 ml of sterile distilled water. STORAGE & SAFETY: Storage Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. Biohazard Information This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling. Usage Assay Information: Usage Recommendations IHC-P:1:50-1:100 GENERAL INFORMATION: Biological Significance The protein encoded by this gene is found on the surface of platelets, monocytes, neutrophils, and some types of T-cells, and makes up a large portion of endothelial cell intercellular junctions. The encoded protein is a member of the immunoglobulin superfamily and is likely involved in leukocyte migration, angiogenesis, and integrin activation.