OVERVIEW: Synonyms Monoclonal HIV1 gp41 antibody, Anti-HIV1 gp41 antibody, HIV gp4 1, Surface protein antibody, HIV1 gp41, gp41 antibody, Human Immunodeficiency Virus 1 antibody, gp41 glycoprotein antibody, Envelope surface glycoprotein gp41 antibody, Glycoprotein 41 antibody, SU antibody, HIV gp4 -1 antibody, HIV-1 gp41 antibody, HIV gp4 1 antibody, gp41 antibody, HIV 1 gp41 antibody, HIV gp4 -1 Specificity HIV-1 gp41 Cross Reactivity To be determined by end-user Applications ELISA, WB Immunogen HIV1 gp41 antibody was raised in mouse using full length recombinant gp41 (HIV-1) as the immunogen. SPECIFICATIONS: Host Mouse Clone 1577 Isotype IgG1 Purity > 90% pure Form & Buffer Supplied lyophilized from PBS buffer, with no preservatives added, reconstitute in sterile distilled water. STORAGE & SAFETY: Storage Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -70 deg C for long term storage. Avoid repeated freeze/thaw cycles. Usage Assay Information: Usage Recommendations Optimal conditions to be determined by end user GENERAL INFORMATION: Biological Significance GP41 is a glycoprotein subunit that remains non-covalently-bound to gp120, and provides the second step by which HIV enters the cell. It is originally buried within the viral envelope, but, when gp120 binds to a CD4, gp120 changes its conformation, causing gp41 to become exposed, where it can assist in fusion with the host cell.